C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) subunit, beta type, 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000425762 PSMB5-005 ENSG00000100804 9606 - 14:23025902-23035230 protein_coding

Homo sapiens EnsemblGRCh38

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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000425762
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000425762 9.270±0.00 2.534±0.00 17.563±0.00 4.889±0.00 7.453±2.03 3.978±0.00 5.520±0.00 14.844±0.00 1.738±0.00 25.036±5.19 20.309±8.60 34.580±7.89 19.060±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006ND CIL_0006ND_0001 CGP 14:22985908-23035230
CIL_0006NC CIL_0006NC_0001 CGP 14:23016543-23044276

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005839 ISS:IEA proteasome core complex
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022803 Psmb5-201 protein_coding Mus_musculus 0 769
ENSMUST00000119744 Psmb5-ps-001 processed_pseudogene Mus_musculus 0 645
ENSMUST00000183617 AC245272.2-201 protein_coding Mus_musculus 0 326
ENSDART00000113111 psmb5-001 protein_coding Danio_rerio 0 276

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