C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor receptor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000124096 Fgfr2-007 ENSMUSG00000030849 10090 - 7:130162451-133123350 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastLiverLungOvaryPlacentaENSMUST00000124096
Transcript ID Bladder Breast Liver Lung Ovary Placenta
ENSMUST00000124096 11.848±2.11 12.555±2.69 3.400±0.80 19.462±2.24 15.958±3.49 6.018±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002WI CIL_0002WI_0002 CGP 7:129591863-133123350
CIL_0007TN CIL_0007TN_0002 VISTA 7:129759548-130361335
CIL_00095T CIL_00095T_0002 VISTA 7:130125765-130727321
CIL_0001BE CIL_0001BE_0002 CGP 7:130162451-133123350

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001525 IGI angiogenesis
GO:0001657 IGI ureteric bud development
GO:0001701 IGI in utero embryonic development
GO:0002053 IGI positive regulation of mesenchymal cell proliferation
GO:0003148 IMP outflow tract septum morphogenesis
GO:0003149 IMP membranous septum morphogenesis
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0007267 IMP cell-cell signaling
GO:0007409 IMP axonogenesis
GO:0007528 IMP neuromuscular junction development
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IGI negative regulation of cell proliferation
GO:0008543 IGI fibroblast growth factor receptor signaling pathway
GO:0008589 IMP regulation of smoothened signaling pathway
GO:0009791 IMP post-embryonic development
GO:0009880 IMP embryonic pattern specification
GO:0009887 IMP organ morphogenesis
GO:0010453 IMP regulation of cell fate commitment
GO:0016331 IMP morphogenesis of embryonic epithelium
GO:0017134 IDA fibroblast growth factor binding
GO:0022612 IMP gland morphogenesis
GO:0030177 IMP positive regulation of Wnt signaling pathway
GO:0030282 IMP bone mineralization
GO:0030324 IMP lung development
GO:0030855 IMP epithelial cell differentiation
GO:0030901 IGI midbrain development
GO:0030916 IMP otic vesicle formation
GO:0031069 IMP hair follicle morphogenesis
GO:0032808 IMP lacrimal gland development
GO:0035264 IMP multicellular organism growth
GO:0035265 IMP organ growth
GO:0040014 IMP regulation of multicellular organism growth
GO:0040036 IMP regulation of fibroblast growth factor receptor signaling pathway
GO:0042127 IMP regulation of cell proliferation
GO:0042472 IMP inner ear morphogenesis
GO:0042476 IMP odontogenesis
GO:0045165 IDA cell fate commitment
GO:0045839 IGI negative regulation of mitosis
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048286 IGI lung alveolus development
GO:0048489 IMP synaptic vesicle transport
GO:0048557 IMP embryonic digestive tract morphogenesis
GO:0048562 IMP embryonic organ morphogenesis
GO:0048565 IMP digestive tract development
GO:0048568 IMP embryonic organ development
GO:0048608 IMP reproductive structure development
GO:0048730 IMP epidermis morphogenesis
GO:0048755 IMP branching morphogenesis of a nerve
GO:0048762 IGI mesenchymal cell differentiation
GO:0050673 IMP epithelial cell proliferation
GO:0050678 IMP regulation of epithelial cell proliferation
GO:0050679 IGI positive regulation of epithelial cell proliferation
GO:0051150 IMP regulation of smooth muscle cell differentiation
GO:0051781 IMP positive regulation of cell division
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060045 IGI positive regulation of cardiac muscle cell proliferation
GO:0060174 IMP limb bud formation
GO:0060348 IMP bone development
GO:0060349 IMP bone morphogenesis
GO:0060365 IMP coronal suture morphogenesis
GO:0060441 IMP epithelial tube branching involved in lung morphogenesis
GO:0060442 IMP branching involved in prostate gland morphogenesis
GO:0060445 IMP branching involved in salivary gland morphogenesis
GO:0060449 IMP bud elongation involved in lung branching
GO:0060463 IMP lung lobe morphogenesis
GO:0060484 IMP lung-associated mesenchyme development
GO:0060501 IMP positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060512 IMP prostate gland morphogenesis
GO:0060523 IMP prostate epithelial cord elongation
GO:0060527 IMP prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060529 IMP squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0060595 IMP fibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO:0060601 IMP lateral sprouting from an epithelium
GO:0060615 IMP mammary gland bud formation
GO:0060664 IGI epithelial cell proliferation involved in salivary gland morphogenesis
GO:0060667 IGI branch elongation involved in salivary gland morphogenesis
GO:0060670 IMP branching involved in labyrinthine layer morphogenesis
GO:0060687 IMP regulation of branching involved in prostate gland morphogenesis
GO:0060688 IMP regulation of morphogenesis of a branching structure
GO:0060915 IGI mesenchymal cell differentiation involved in lung development
GO:0060916 IMP mesenchymal cell proliferation involved in lung development
GO:0061031 IMP endodermal digestive tract morphogenesis
GO:0070307 IGI lens fiber cell development
GO:0070372 IMP regulation of ERK1 and ERK2 cascade
GO:0070374 IGI positive regulation of ERK1 and ERK2 cascade
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000326324 FGFR1-008 protein_coding Homo_sapiens 0 357
ENST00000335922 FGFR1-003 protein_coding Homo_sapiens 0 357
ENST00000336553 FGFR2-003 protein_coding Homo_sapiens 0 573
ENST00000346997 FGFR2-009 protein_coding Homo_sapiens 0 832
ENST00000351936 FGFR2-201 protein_coding Homo_sapiens 0 832
ENST00000356207 FGFR1-004 protein_coding Homo_sapiens 0 357
ENST00000356226 FGFR2-012 protein_coding Homo_sapiens 0 1709
ENST00000357555 FGFR2-202 protein_coding Homo_sapiens 0 785
ENST00000358487 FGFR2-001 protein_coding Homo_sapiens 0 1749
ENST00000360144 FGFR2-004 protein_coding Homo_sapiens 0 604
ENST00000369056 FGFR2-006 protein_coding Homo_sapiens 0 604
ENST00000369058 FGFR2-011 protein_coding Homo_sapiens 0 604
ENST00000369059 FGFR2-007 protein_coding Homo_sapiens 0 998
ENST00000369060 FGFR2-005 protein_coding Homo_sapiens 0 1526
ENST00000369061 FGFR2-203 protein_coding Homo_sapiens 0 1749
ENST00000397091 FGFR1-001 protein_coding Homo_sapiens 0 357
ENST00000397103 FGFR1-011 protein_coding Homo_sapiens 0 357
ENST00000397108 FGFR1-020 protein_coding Homo_sapiens 0 357
ENST00000397113 FGFR1-012 protein_coding Homo_sapiens 0 357
ENST00000425967 FGFR1-202 protein_coding Homo_sapiens 0 357
ENST00000429361 FGFR2-021 protein_coding Homo_sapiens 0 460
ENST00000447712 FGFR1-203 protein_coding Homo_sapiens 0 357
ENST00000457416 FGFR2-010 protein_coding Homo_sapiens 0 832
ENST00000467584 FGFR2-020 processed_transcript Homo_sapiens 0 305
ENST00000478859 FGFR2-008 protein_coding Homo_sapiens 0 1749
ENST00000526570 FGFR1-024 retained_intron Homo_sapiens 0 357
ENST00000527114 FGFR1-025 retained_intron Homo_sapiens 3e-19 100
ENST00000531196 FGFR1-039 nonsense_mediated_decay Homo_sapiens 0 307
ENST00000532791 FGFR1-002 protein_coding Homo_sapiens 0 357
ENST00000533619 FGFR1-030 retained_intron Homo_sapiens 3e-21 106
ENST00000604236 FGFR2-024 nonsense_mediated_decay Homo_sapiens 0 1519
ENST00000613048 FGFR2-204 protein_coding Homo_sapiens 0 1749

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