C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: son of sevenless homolog 1 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000426016 SOS1-001 ENSG00000115904 9606 - 2:38981396-39121051 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartOvaryENST00000426016
Transcript ID Colon Heart Ovary
ENST00000426016 2.476±0.00 0.433±0.00 4.008±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000675 CIL_000675_0001 CGP 2:38981396-39229588

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005088 EXP Ras guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005100 TAS Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0007165 NAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007264 TAS:IEA small GTPase mediated signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0014069 IEA postsynaptic density
GO:0017124 IEA SH3 domain binding
GO:0030168 TAS platelet activation
GO:0032320 TAS positive regulation of Ras GTPase activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043025 IEA neuronal cell body
GO:0043065 TAS positive regulation of apoptotic process
GO:0045087 TAS innate immune response
GO:0045742 IEA positive regulation of epidermal growth factor receptor signaling pathway
GO:0046982 IEA protein heterodimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050900 TAS leukocyte migration
GO:0051056 TAS:IEA regulation of small GTPase mediated signal transduction
GO:0051057 IEA positive regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000068714 Sos1-201 protein_coding Mus_musculus 0 4542

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