C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000431183 SMPD4-201 ENSG00000136699 9606 - 2:130151392-130181757 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004767 TAS sphingomyelin phosphodiesterase activity
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005794 IDA Golgi apparatus
GO:0005802 IDA trans-Golgi network
GO:0006665 TAS sphingolipid metabolic process
GO:0006685 IDA sphingomyelin catabolic process
GO:0006687 TAS glycosphingolipid metabolic process
GO:0016021 IEA integral component of membrane
GO:0044281 TAS small molecule metabolic process
GO:0046475 IDA glycerophospholipid catabolic process
GO:0046513 IDA ceramide biosynthetic process
GO:0046872 IEA metal ion binding
GO:0050290 IDA sphingomyelin phosphodiesterase D activity
GO:0071356 IDA cellular response to tumor necrosis factor

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000170273 Smpd4-014 protein_coding Mus_musculus 0 2189
ENSMUST00000170401 Smpd4-006 retained_intron Mus_musculus 0 2032
ENSMUST00000163476 Smpd4-002 protein_coding Mus_musculus 0 2028
ENSMUST00000165363 Smpd4-003 protein_coding Mus_musculus 0 2013
ENSMUST00000170366 Smpd4-009 protein_coding Mus_musculus 0 1624
ENSMUST00000163997 Smpd4-011 protein_coding Mus_musculus 0 1552
ENSMUST00000166091 Smpd4-005 retained_intron Mus_musculus 0 1546
ENSMUST00000170117 Smpd4-012 nonsense_mediated_decay Mus_musculus 0 1447
ENSMUST00000006053 Smpd4-001 protein_coding Mus_musculus 0 1447
ENSMUST00000170996 Smpd4-007 protein_coding Mus_musculus 0 1266
ENSMUST00000090159 Smpd4-004 protein_coding Mus_musculus 0 1075
ENSMUST00000164292 Smpd4-022 retained_intron Mus_musculus 0 750
ENSMUST00000167217 Smpd4-010 nonsense_mediated_decay Mus_musculus 0 628
ENSMUST00000167362 Smpd4-013 processed_transcript Mus_musculus 0 316
ENSMUST00000167592 Smpd4-020 retained_intron Mus_musculus 0 296
ENSMUST00000163592 Smpd4-015 protein_coding Mus_musculus 9.99967e-42 176
ENSMUST00000172182 Smpd4-021 protein_coding Mus_musculus 9.99967e-42 176
ENSMUST00000169662 Smpd4-018 protein_coding Mus_musculus 9.99967e-42 176
ENSMUST00000171435 Smpd4-019 protein_coding Mus_musculus 4.99997e-41 174
ENSMUST00000165092 Smpd4-016 protein_coding Mus_musculus 4e-27 128
ENSMUST00000166322 Smpd4-023 retained_intron Mus_musculus 1e-26 126
ENSMUST00000168101 Smpd4-008 protein_coding Mus_musculus 3e-23 115

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