C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: endoplasmic reticulum to nucleus signaling 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000433197 ERN1-001 ENSG00000178607 9606 - 17:64039142-64130125 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000433197
Transcript ID Adipose Adrenal Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000433197 1.213±0.00 1.333±0.00 0.288±0.00 0.626±0.16 0.446±0.31 0.750±0.00 0.861±0.53 1.568±0.49 0.759±0.09 2.044±1.70 0.850±0.14 0.757±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006GW CIL_0006GW_0001 CGP 17:64002594-64130819
CIL_0004WB CIL_0004WB_0002 CGP 17:64039142-64263301

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004519 IEA endonuclease activity
GO:0004521 IDA endoribonuclease activity
GO:0004540 IEA ribonuclease activity
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005637 IEA nuclear inner membrane
GO:0005739 IEA mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006397 IEA mRNA processing
GO:0006468 IDA:IEA protein phosphorylation
GO:0006987 IDA activation of signaling protein activity involved in unfolded protein response
GO:0007050 ISS cell cycle arrest
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019899 IPI enzyme binding
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0042802 IPI identical protein binding
GO:0044267 TAS cellular protein metabolic process
GO:0046777 IEA protein autophosphorylation
GO:0070055 IDA HAC1-type intron splice site recognition and cleavage
GO:0070059 IEA intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis
GO:0090502 IDA RNA phosphodiester bond hydrolysis, endonucleolytic
GO:1900103 IMP positive regulation of endoplasmic reticulum unfolded protein response

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001059 Ern1-001 protein_coding Mus_musculus 0 3727
ENSMUST00000131895 Ern1-003 processed_transcript Mus_musculus 0 2287
ENSMUST00000106801 Ern1-002 protein_coding Mus_musculus 0 1613
ENSMUST00000106800 Ern1-005 protein_coding Mus_musculus 0 351
ENSMUST00000077549 Prss43-201 protein_coding Mus_musculus 0.00000000003 77
ENSMUST00000048099 Tmem194-001 protein_coding Mus_musculus 0.000003 60

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