C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: protein kinase D2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000433867 PRKD2-201 ENSG00000105287 9606 - 19:46674317-46717127 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000433867
Transcript ID Adipose Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000433867 6.428±0.00 3.081±0.00 1.791±0.00 3.055±0.00 0.940±0.00 24.375±0.00 8.294±2.91 9.675±0.66 4.520±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001938 IMP positive regulation of endothelial cell proliferation
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 NAS protein serine/threonine kinase activity
GO:0004697 IEA protein kinase C activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006468 IEA:NAS protein phosphorylation
GO:0007155 IEA cell adhesion
GO:0008219 IMP cell death
GO:0010595 IMP positive regulation of endothelial cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0030949 IMP positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032743 ISS positive regulation of interleukin-2 production
GO:0032757 IMP positive regulation of interleukin-8 production
GO:0032793 IGI positive regulation of CREB transcription factor activity
GO:0033138 IGI positive regulation of peptidyl-serine phosphorylation
GO:0035556 IMP:IEA intracellular signal transduction
GO:0035924 IMP cellular response to vascular endothelial growth factor stimulus
GO:0038033 IMP positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0043536 IMP positive regulation of blood vessel endothelial cell migration
GO:0045743 IMP positive regulation of fibroblast growth factor receptor signaling pathway
GO:0045766 IMP positive regulation of angiogenesis
GO:0045785 IMP positive regulation of cell adhesion
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046777 IDA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0048010 IMP vascular endothelial growth factor receptor signaling pathway
GO:0050852 IDA T cell receptor signaling pathway
GO:0050862 ISS positive regulation of T cell receptor signaling pathway
GO:0051091 IMP positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0061154 TAS endothelial tube morphogenesis
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:1901727 IGI positive regulation of histone deacetylase activity
GO:1902533 IMP positive regulation of intracellular signal transduction
GO:2000573 ISS positive regulation of DNA biosynthetic process
GO:2001028 IMP positive regulation of endothelial cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168093 Prkd2-202 protein_coding Mus_musculus 0 3179
ENSMUST00000086104 Prkd2-201 protein_coding Mus_musculus 0 3179
ENSMUST00000168887 Prkd3-201 protein_coding Mus_musculus 0 564
ENSMUST00000118768 Prkd3-004 protein_coding Mus_musculus 0 564
ENSMUST00000119284 Prkd3-002 protein_coding Mus_musculus 0 564
ENSMUST00000003191 Prkd3-001 protein_coding Mus_musculus 0 564

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