C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000439383 PSMD2-003 ENSG00000175166 9606 + 3:184300581-184309048 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000439383
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000439383 37.206±0.00 40.182±0.00 5.126±0.00 12.272±6.42 28.147±20.17 19.392±13.52 21.181±18.53 18.951±15.08 21.215±0.00 14.362±10.83 76.361±63.66 69.991±49.40 61.953±16.41 80.780±13.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G3 CIL_0005G3_0001 CGP 3:184135038-184684758
CIL_000571 CIL_000571_0001 CGP 3:184259213-184309054
CIL_000572 CIL_000572_0001 CGP 3:184298709-184335358

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA:IEA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005838 TAS proteasome regulatory particle
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0022624 ISS proteasome accessory complex
GO:0030234 IEA enzyme regulator activity
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042176 IEA regulation of protein catabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000172207 Psmd2-002 nonsense_mediated_decay Mus_musculus 0 3256
ENSMUST00000007212 Psmd2-001 protein_coding Mus_musculus 0 3256
ENSMUST00000050717 Gm5422-201 protein_coding Mus_musculus 0 3031
ENSDART00000126218 psmd2-201 protein_coding Danio_rerio 0 1020
ENSMUST00000169184 Psmd2-007 processed_transcript Mus_musculus 0 787
ENSMUST00000166071 Psmd2-006 processed_transcript Mus_musculus 0 370

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