C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000441946 PSME3-004 ENSG00000131467 9606 + 17:42833418-42843216 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000441946
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000441946 19.358±0.00 19.330±0.00 2.242±0.00 13.542±9.07 16.303±0.00 8.418±1.23 9.120±0.00 13.731±11.34 8.761±4.76 8.000±0.00 7.417±4.41 38.061±26.11 13.954±1.65 22.133±3.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005S8 CIL_0005S8_0001 CGP 17:42798792-42833350
CIL_0005S9 CIL_0005S9_0001 CGP 17:42810134-42843758
CIL_0004MA CIL_0004MA_0001 CGP 17:42824385-42850707

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 TAS proteasome complex
GO:0002039 IDA p53 binding
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008537 IEA proteasome activator complex
GO:0010467 TAS gene expression
GO:0010950 IDA positive regulation of endopeptidase activity
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0061133 IDA endopeptidase activator activity
GO:0061136 IDA regulation of proteasomal protein catabolic process
GO:0097371 IDA MDM2/MDM4 family protein binding
GO:2001237 IDA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000019470 Psme3-001 protein_coding Mus_musculus 0 1964
ENSMUST00000131170 Psme3-005 processed_transcript Mus_musculus 0 1086
ENSMUST00000151385 Psme3-003 protein_coding Mus_musculus 0 881
ENSMUST00000142640 Psme3-002 protein_coding Mus_musculus 0 612
ENSMUST00000127998 Psme3-004 processed_transcript Mus_musculus 0 460

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