C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000443617 HERC1-001 ENSG00000103657 9606 - 15:63608618-63833888 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000443617
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000443617 1.249±0.00 1.318±0.00 2.452±0.00 6.161±3.47 1.419±0.00 2.274±1.13 2.923±1.05 3.353±0.00 3.408±2.30 4.203±2.12 2.007±1.36 0.525±0.03 2.190±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00050A CIL_00050A_0002 CGP 15:63608618-64072033

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005086 TAS ARF guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005737 TAS cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0006810 IEA transport
GO:0010507 IEA negative regulation of autophagy
GO:0016020 IEA membrane
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0021702 IEA cerebellar Purkinje cell differentiation
GO:0031175 IEA neuron projection development
GO:0043547 IEA positive regulation of GTPase activity
GO:0050885 IEA neuromuscular process controlling balance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000042824 Herc1-001 protein_coding Mus_musculus 0 20830
ENSMUST00000135159 Herc1-007 protein_coding Mus_musculus 0 2326
ENSDART00000109030 HERC1-201 protein_coding Danio_rerio 0 1947
ENSMUST00000140487 Herc1-003 retained_intron Mus_musculus 0 1461
ENSMUST00000144280 Herc1-002 retained_intron Mus_musculus 0 1423
ENSMUST00000124969 Herc1-004 retained_intron Mus_musculus 0 1096
ENSMUST00000130854 Herc1-006 retained_intron Mus_musculus 0 948
ENSMUST00000056890 Fbxl22-201 protein_coding Mus_musculus 0 416
ENSMUST00000135600 Herc1-005 retained_intron Mus_musculus 0 318

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