C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: beta-site APP-cleaving enzyme 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000445823 BACE1-004 ENSG00000186318 9606 - 11:117289535-117315798 protein_coding

Homo sapiens EnsemblGRCh38

Genome
Exciting message
Genes
Structures from Ensembl
Connecting
Transcripts
Structures from Ensembl
Connecting
Powered by Dalliance 0.11.11

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001540 IPI beta-amyloid binding
GO:0004190 IEA:IDA aspartic-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005768 IDA endosome
GO:0005770 IDA late endosome
GO:0005771 IDA multivesicular body
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005802 IDA trans-Golgi network
GO:0005886 IDA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006508 IEA:IDA proteolysis
GO:0006509 TAS membrane protein ectodomain proteolysis
GO:0008798 TAS beta-aspartyl-peptidase activity
GO:0016021 NAS integral component of membrane
GO:0019899 IPI enzyme binding
GO:0050435 IDA beta-amyloid metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000159970 Bace1-003 retained_intron Mus_musculus 0 1291
ENSMUST00000034591 Bace1-001 protein_coding Mus_musculus 0 1291
ENSMUST00000162587 Bace1-006 protein_coding Mus_musculus 0 1203
ENSMUST00000078111 Bace1-002 protein_coding Mus_musculus 0 802
ENSMUST00000162559 Bace1-005 processed_transcript Mus_musculus 0 255
ENSMUST00000159499 Bace1-004 nonsense_mediated_decay Mus_musculus 0 235

Loading