C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: beta-site APP cleaving enzyme 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034591 Bace1-001 ENSMUSG00000032086 10090 + 9:45838580-45864399 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainLiverMusclePlacentaENSMUST00000034591
Transcript ID Adrenal Brain Liver Muscle Placenta
ENSMUST00000034591 6.386±0.00 12.316±0.41 5.292±1.43 3.338±0.37 5.129±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RC CIL_0007RC_0002 VISTA 9:45818249-46421546

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001540 IEA beta-amyloid binding
GO:0004175 IDA endopeptidase activity
GO:0004190 ISS aspartic-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005768 ISS endosome
GO:0005770 IEA late endosome
GO:0005771 IEA multivesicular body
GO:0005783 IEA endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005802 IEA trans-Golgi network
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006508 ISS proteolysis
GO:0008233 IEA peptidase activity
GO:0016020 IDA membrane
GO:0019899 IEA enzyme binding
GO:0030424 IDA axon
GO:0031410 IDA cytoplasmic vesicle
GO:0050435 ISS beta-amyloid metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000313005 BACE1-001 protein_coding Homo_sapiens 0 2615
ENST00000392937 BACE1-006 protein_coding Homo_sapiens 0 1997
ENST00000428381 BACE1-002 protein_coding Homo_sapiens 0 1203
ENST00000445823 BACE1-004 protein_coding Homo_sapiens 0 1291
ENST00000504995 BACE1-008 protein_coding Homo_sapiens 0 782
ENST00000509916 BACE1-010 retained_intron Homo_sapiens 0 566
ENST00000510630 BACE1-007 protein_coding Homo_sapiens 0 1242
ENST00000510915 BACE1-009 protein_coding Homo_sapiens 0 695
ENST00000513780 BACE1-003 protein_coding Homo_sapiens 0 1203
ENST00000514464 BACE1-005 processed_transcript Homo_sapiens 0 484
ENST00000528053 BACE1-013 protein_coding Homo_sapiens 0 1297
ENST00000530824 BACE1-016 retained_intron Homo_sapiens 0 726
ENST00000530849 RNF214-004 protein_coding Homo_sapiens 0 305

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