C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: microphthalmia-associated transcription factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000448226 MITF-007 ENSG00000187098 9606 + 3:69739471-69966029 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; MuscleENST00000448226
Transcript ID Muscle
ENST00000448226 1.366±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001TC CIL_0001TC_0002 CGP 3:69169990-69968337

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001227 NAS RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0005515 IPI protein binding
GO:0005634 NAS nucleus
GO:0006355 NAS:IEA regulation of transcription, DNA-templated
GO:0006461 IDA protein complex assembly
GO:0030318 NAS melanocyte differentiation
GO:0043234 IDA protein complex
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000043637 Mitf-001 protein_coding Mus_musculus 0 2488
ENSMUST00000113339 Mitf-005 protein_coding Mus_musculus 0 2266
ENSMUST00000101123 Mitf-003 protein_coding Mus_musculus 0 2261
ENSMUST00000043628 Mitf-006 protein_coding Mus_musculus 0 1853
ENSMUST00000139462 Mitf-007 nonsense_mediated_decay Mus_musculus 0 1332
ENSMUST00000148233 Mitf-002 retained_intron Mus_musculus 0 628

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