C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cathepsin S
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000448301 CTSS-006 ENSG00000163131 9606 - 1:150732567-150765792 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000448301
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000448301 20.316±0.00 27.432±0.00 1.560±0.00 3.075±0.81 26.944±9.68 17.269±6.81 4.697±1.14 15.242±7.21 11.521±0.47 76.733±8.49 1.109±0.43 11.884±3.01 18.679±7.60 5.797±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001968 IPI fibronectin binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002250 IEP adaptive immune response
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0004197 IDA cysteine-type endopeptidase activity
GO:0005518 IDA collagen binding
GO:0005576 NAS extracellular region
GO:0005615 IDA extracellular space
GO:0005764 IDA lysosome
GO:0006508 TAS:IEA proteolysis
GO:0006955 TAS immune response
GO:0008234 IEA cysteine-type peptidase activity
GO:0019882 TAS antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030574 IDA collagen catabolic process
GO:0034769 IDA basement membrane disassembly
GO:0036021 TAS endolysosome lumen
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043202 TAS lysosomal lumen
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043236 IDA laminin binding
GO:0043394 IPI proteoglycan binding
GO:0045087 TAS innate immune response
GO:0051603 IDA proteolysis involved in cellular protein catabolic process
GO:0097067 IEP cellular response to thyroid hormone stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000116304 Ctss-201 protein_coding Mus_musculus 0 593
ENSMUST00000015667 Ctss-001 protein_coding Mus_musculus 0 593

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