C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SUMO1/sentrin specific peptidase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000448372 SENP1-002 ENSG00000079387 9606 - 12:48042974-48105808 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastKidneyLiverOvaryPlacentaTestisENST00000448372
Transcript ID Adrenal Bladder Breast Kidney Liver Ovary Placenta Testis
ENST00000448372 2.727±0.00 1.800±0.00 2.136±0.28 0.205±0.00 1.141±0.32 4.214±1.24 1.734±0.00 43.780±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079B CIL_00079B_0001 CGP 12:47972965-48106308
CIL_00068J CIL_00068J_0001 CGP 12:48042898-48146404

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004175 TAS endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005925 IDA focal adhesion
GO:0006508 IEA proteolysis
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008234 IEA cysteine-type peptidase activity
GO:0010724 IEA regulation of definitive erythrocyte differentiation
GO:0016925 TAS protein sumoylation
GO:0016926 IMP protein desumoylation
GO:0016929 ISS SUMO-specific protease activity
GO:0031965 IDA nuclear membrane
GO:0032435 IEA negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0097190 IMP apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000044189 Senp1-001 protein_coding Mus_musculus 0 2499
ENSMUST00000180716 Senp1-003 nonsense_mediated_decay Mus_musculus 0 2316
ENSMUST00000180657 Senp1-002 protein_coding Mus_musculus 0 1522
ENSMUST00000181855 Senp1-005 retained_intron Mus_musculus 0 1522
ENSMUST00000181349 Senp1-004 retained_intron Mus_musculus 0 985
ENSMUST00000120326 Gm13928-001 processed_pseudogene Mus_musculus 0 874
ENSMUST00000180461 Senp1-007 processed_transcript Mus_musculus 0 688

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