C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: twist family bHLH transcription factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000448943 TWIST2-001 ENSG00000233608 9606 + 2:238848032-238887252 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartLiverLungENST00000448943
Transcript ID Brain Breast Colon Heart Liver Lung
ENST00000448943 0.013±0.00 0.593±0.00 0.212±0.00 0.076±0.00 0.096±0.05 0.375±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003NF CIL_0003NF_0001 CGP 2:238426742-238910543
CIL_0007UT CIL_0007UT_0001 VISTA 2:238792799-239398211
CIL_0003NG CIL_0003NG_0001 CGP 2:238848032-239401654

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007275 IEA multicellular organismal development
GO:0030154 IEA cell differentiation
GO:0045668 IDA negative regulation of osteoblast differentiation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000007949 Twist2-001 protein_coding Mus_musculus 0 1033
ENSMUST00000186075 Twist2-002 protein_coding Mus_musculus 0 1016
ENSMUST00000049089 Twist1-201 protein_coding Mus_musculus 0 390
ENSDART00000011146 twist3-201 protein_coding Danio_rerio 0 281

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