C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000503431 UCHL1-005 ENSG00000154277 9606 + 4:41256769-41268256 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000503431
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000503431 6.903±0.00 3.345±0.00 0.461±0.00 226.074±177.75 53.510±0.00 14.916±11.79 1.926±0.00 55.728±0.00 3.017±0.00 1.716±0.00 4.259±4.44 3.231±1.57 10.469±4.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038S CIL_00038S_0001 CGP 4:40810027-41268455
CIL_00038J CIL_00038J_0001 CGP 4:41256413-41700044

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004197 IDA cysteine-type endopeptidase activity
GO:0004221 TAS ubiquitin thiolesterase activity
GO:0004843 IEA ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008219 IEA cell death
GO:0008242 IDA omega peptidase activity
GO:0016579 IDA protein deubiquitination
GO:0016874 IEA ligase activity
GO:0031694 IPI alpha-2A adrenergic receptor binding
GO:0043130 IDA ubiquitin binding
GO:0043161 NAS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031131 Uchl1-001 protein_coding Mus_musculus 0 821
ENSMUST00000176015 Uchl1-002 retained_intron Mus_musculus 0 732

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