C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MCF.2 cell line derived transforming sequence
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000520602 MCF2-001 ENSG00000101977 9606 - X:139581770-139692156 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalHeartKidneyTestisENST00000520602
Transcript ID Adrenal Heart Kidney Testis
ENST00000520602 0.023±0.00 0.009±0.00 0.044±0.00 0.542±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000PO CIL_0000PO_0002 CGP X:139530758-139708227
CIL_0000PN CIL_0000PN_0002 CGP X:139581770-139945276

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005856 TAS cytoskeleton
GO:0007264 TAS small GTPase mediated signal transduction
GO:0016020 IEA membrane
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000063507 Mcf2-001 protein_coding Mus_musculus 0 2712
ENSMUST00000101531 Mcf2-003 protein_coding Mus_musculus 0 2241
ENSMUST00000033478 Mcf2-002 protein_coding Mus_musculus 0 1297

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