C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingomyelin phosphodiesterase 1, acid lysosomal
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000527275 SMPD1-008 ENSG00000166311 9606 + 11:6390475-6394778 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderColonLungOvaryENST00000527275
Transcript ID Bladder Colon Lung Ovary
ENST00000527275 1.379±0.00 1.549±0.00 1.418±0.00 1.237±0.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079D CIL_00079D_0001 CGP 11:6318946-6394998
CIL_0004AE CIL_0004AE_0001 CGP 11:6390431-6419414

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004767 IEA sphingomyelin phosphodiesterase activity
GO:0005515 IPI protein binding
GO:0006665 TAS sphingolipid metabolic process
GO:0006684 TAS sphingomyelin metabolic process
GO:0006685 IEA sphingomyelin catabolic process
GO:0006687 TAS glycosphingolipid metabolic process
GO:0007165 TAS signal transduction
GO:0007399 TAS nervous system development
GO:0008219 IEA cell death
GO:0016787 IEA hydrolase activity
GO:0016798 IEA hydrolase activity, acting on glycosyl bonds
GO:0023021 IMP termination of signal transduction
GO:0035307 IMP positive regulation of protein dephosphorylation
GO:0043202 TAS lysosomal lumen
GO:0043407 IMP negative regulation of MAP kinase activity
GO:0044281 TAS small molecule metabolic process
GO:0046513 IMP ceramide biosynthetic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000046983 Smpd1-201 protein_coding Mus_musculus 0 1690

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