C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: amyloid beta (A4) precursor-like protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000528499 APLP2-003 ENSG00000084234 9606 + 11:130069894-130143806 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartLungMuscleOvaryENST00000528499
Transcript ID Breast Heart Lung Muscle Ovary
ENST00000528499 7.573±0.00 6.527±0.00 16.207±0.00 2.796±0.00 33.570±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000511 CIL_000511_0002 CGP 11:129899706-130144811
CIL_000510 CIL_000510_0002 CGP 11:130069837-130210376

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 NAS DNA binding
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005886 IEA plasma membrane
GO:0007186 NAS G-protein coupled receptor signaling pathway
GO:0008201 IEA heparin binding
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0016020 IDA membrane
GO:0016021 NAS integral component of membrane
GO:0042802 IPI identical protein binding
GO:0046914 IEA transition metal ion binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000079758 Aplp2-202 protein_coding Mus_musculus 0 2006
ENSMUST00000072634 Aplp2-201 protein_coding Mus_musculus 0 1718
ENSDART00000077125 aplp2-001 protein_coding Danio_rerio 0 678

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