C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000532993 ARHGEF12-003 ENSG00000196914 9606 + 11:120385294-120489034 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000532993
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000532993 10.825±0.00 10.155±3.11 7.388±0.00 7.599±2.95 4.824±0.28 10.948±4.42 3.484±0.00 8.450±2.46 7.446±3.22 6.115±0.00 6.024±2.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00021Z CIL_00021Z_0002 CGP 11:120325129-120489936

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000165665 Arhgef12-202 protein_coding Mus_musculus 0 6233
ENSMUST00000072767 Arhgef12-201 protein_coding Mus_musculus 0 5945

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