C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: neuroligin 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000536169 NLGN3-201 ENSG00000196338 9606 + X:71144831-71171199 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastKidneyLiverOvaryPlacentaTestisENST00000536169
Transcript ID Adipose Brain Breast Kidney Liver Ovary Placenta Testis
ENST00000536169 0.172±0.00 4.205±2.88 0.233±0.13 0.172±0.00 0.019±0.00 1.639±1.28 0.268±0.08 1.229±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00057X CIL_00057X_0001 CGP X:71118556-71171201
CIL_00057N CIL_00057N_0001 CGP X:71144831-71225516

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002087 ISS regulation of respiratory gaseous exchange by neurological system process
GO:0004872 ISS receptor activity
GO:0005515 IPI protein binding
GO:0005887 ISS integral component of plasma membrane
GO:0006898 ISS receptor-mediated endocytosis
GO:0007158 ISS neuron cell-cell adhesion
GO:0007416 ISS synapse assembly
GO:0007612 IMP learning
GO:0008152 IEA metabolic process
GO:0009986 IDA cell surface
GO:0016787 IEA hydrolase activity
GO:0030054 IEA cell junction
GO:0030139 ISS endocytic vesicle
GO:0030534 IMP adult behavior
GO:0035176 IMP social behavior
GO:0042043 IBA neurexin family protein binding
GO:0045202 ISS synapse
GO:0048675 ISS axon extension
GO:0050804 ISS regulation of synaptic transmission
GO:0050808 IMP synapse organization
GO:0050839 ISS cell adhesion molecule binding
GO:0051965 ISS positive regulation of synapse assembly
GO:0051968 ISS positive regulation of synaptic transmission, glutamatergic
GO:0060024 ISS rhythmic synaptic transmission
GO:0060076 IDA excitatory synapse
GO:0060080 ISS regulation of inhibitory postsynaptic membrane potential
GO:0071625 IMP vocalization behavior
GO:0097104 ISS postsynaptic membrane assembly
GO:0097105 ISS presynaptic membrane assembly
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential
GO:2000969 ISS positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000065858 Nlgn3-001 protein_coding Mus_musculus 0 3672
ENSMUST00000151528 Nlgn3-004 protein_coding Mus_musculus 0 3672
ENSMUST00000118111 Nlgn3-002 protein_coding Mus_musculus 0 3672
ENSMUST00000130555 Nlgn3-003 protein_coding Mus_musculus 0 2732
ENSDART00000112978 nlgn2a-201 protein_coding Danio_rerio 0 621
ENSMUST00000144860 Nlgn3-007 processed_transcript Mus_musculus 0 555
ENSDART00000125284 nlgn2a-202 protein_coding Danio_rerio 0 544
ENSMUST00000147443 Nlgn3-006 processed_transcript Mus_musculus 0 374

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