C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: LIM domain kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000538333 LIMK1-005 ENSG00000106683 9606 + 7:74093079-74121458 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonOvaryENST00000538333
Transcript ID Breast Colon Ovary
ENST00000538333 2.157±0.00 1.275±0.00 4.889±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 NAS:IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IDA:IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007266 TAS Rho protein signal transduction
GO:0007399 TAS nervous system development
GO:0007411 TAS axon guidance
GO:0008270 IEA zinc ion binding
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0030036 TAS actin cytoskeleton organization
GO:0031072 IDA heat shock protein binding
GO:0032233 IDA positive regulation of actin filament bundle assembly
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043005 ISS neuron projection
GO:0045087 TAS innate immune response
GO:0045773 ISS positive regulation of axon extension
GO:0051444 IDA negative regulation of ubiquitin-protein transferase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000111233 Limk1-002 protein_coding Mus_musculus 0 2084
ENSMUST00000015137 Limk1-001 protein_coding Mus_musculus 0 2069
ENSMUST00000134093 Limk1-004 nonsense_mediated_decay Mus_musculus 0 1506
ENSMUST00000132027 Limk1-003 retained_intron Mus_musculus 0 850
ENSMUST00000137897 Limk1-005 retained_intron Mus_musculus 0 497
ENSMUST00000138590 Limk1-006 protein_coding Mus_musculus 0 217

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