C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: malate dehydrogenase 1, NAD (soluble)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000539945 MDH1-201 ENSG00000014641 9606 + 2:63589151-63607194 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000539945
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000539945 5.995±0.00 18.064±0.00 11.327±0.00 42.763±0.00 34.693±0.00 10.036±0.00 130.164±0.00 47.381±0.00 16.591±0.00 14.486±0.00 7.322±0.00 33.706±0.00 29.219±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000100 CIL_000100_0002 CGP 2:63050057-63827843
CIL_000105 CIL_000105_0002 CGP 2:63588609-63891562

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004470 TAS malic enzyme activity
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005975 IEA:TAS carbohydrate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006094 TAS gluconeogenesis
GO:0006099 IEA tricarboxylic acid cycle
GO:0006107 IEA oxaloacetate metabolic process
GO:0006108 IEA malate metabolic process
GO:0006734 IEA NADH metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0016615 IEA malate dehydrogenase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0019674 IEA NAD metabolic process
GO:0030060 IEA:TAS L-malate dehydrogenase activity
GO:0044262 IEA cellular carbohydrate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0047860 IEA diiodophenylpyruvate reductase activity
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102874 Mdh1-001 protein_coding Mus_musculus 0 1369
ENSMUST00000125302 Mdh1-002 protein_coding Mus_musculus 0 640
ENSMUST00000144978 Mdh1-003 processed_transcript Mus_musculus 0 592
ENSMUST00000146146 Mdh1-004 processed_transcript Mus_musculus 0 239

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