C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000540499 IDH2-004 ENSG00000182054 9606 - 15:90084177-90100695 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000540499
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000540499 7.979±0.00 12.065±0.00 5.243±0.00 19.748±16.58 12.642±7.39 17.153±5.46 89.535±61.71 79.380±0.00 102.442±0.00 16.607±0.00 138.559±88.92 19.911±19.28 65.422±13.65 7.489±5.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001T4 CIL_0001T4_0002 CGP 15:90001392-90102504
CIL_00079J CIL_00079J_0001 CGP 15:90083045-90229679

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0004450 ISS:IEA isocitrate dehydrogenase (NADP+) activity
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005975 NAS carbohydrate metabolic process
GO:0006097 IEA glyoxylate cycle
GO:0006099 TAS tricarboxylic acid cycle
GO:0006102 ISS:IEA isocitrate metabolic process
GO:0006103 ISS 2-oxoglutarate metabolic process
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107384 Idh2-001 protein_coding Mus_musculus 0 1650
ENSMUST00000134328 Idh2-002 nonsense_mediated_decay Mus_musculus 0 918
ENSMUST00000139178 Idh2-005 retained_intron Mus_musculus 0 734
ENSMUST00000125542 Idh2-003 processed_transcript Mus_musculus 0 593
ENSMUST00000156761 Idh2-006 retained_intron Mus_musculus 0 392
ENSMUST00000134070 Idh2-004 retained_intron Mus_musculus 0 346

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