C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein inhibitor of activated STAT, 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000545237 PIAS1-002 ENSG00000033800 9606 + 15:68054576-68188064 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000545237
Transcript ID Bladder Brain Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000545237 2.873±0.00 6.995±0.00 4.154±1.04 4.264±0.00 5.523±3.55 6.373±0.74 2.468±0.73 5.584±1.26 3.785±0.13 9.692±0.83

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DX CIL_0008DX_0001 VISTA 15:67486945-68088375
CIL_00098T CIL_00098T_0001 VISTA 15:67539824-68142788
CIL_0008FO CIL_0008FO_0001 VISTA 15:67583922-68185582
CIL_0004L4 CIL_0004L4_0002 CGP 15:67819704-68198603

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003713 NAS transcription coactivator activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007259 TAS JAK-STAT cascade
GO:0008270 IEA zinc ion binding
GO:0016605 ISS PML body
GO:0016925 ISS protein sumoylation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019789 IDA SUMO ligase activity
GO:0019899 IPI enzyme binding
GO:0030521 NAS androgen receptor signaling pathway
GO:0032436 ISS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033235 IDA positive regulation of protein sumoylation
GO:0042127 ISS regulation of cell proliferation
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0050681 NAS androgen receptor binding
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060334 TAS regulation of interferon-gamma-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098651 Pias1-201 protein_coding Mus_musculus 0 2839
ENSDART00000090310 pias1b-001 protein_coding Danio_rerio 0.0000000005 71

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