C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein arginine methyltransferase 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000553897 PRMT5-010 ENSG00000100462 9606 - 14:22920876-22929408 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000553897
Transcript ID Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000553897 1.652±0.00 4.633±0.00 2.237±1.45 1.439±0.00 3.058±0.00 2.237±0.00 12.831±0.00 5.043±2.89 5.333±0.84

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006WJ CIL_0006WJ_0001 CGP 14:22920511-22957161

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000387 IMP spliceosomal snRNP assembly
GO:0001046 ISS core promoter sequence-specific DNA binding
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IBA regulation of transcription, DNA-templated
GO:0006479 IEA protein methylation
GO:0007088 TAS regulation of mitosis
GO:0008168 IEA:IDA methyltransferase activity
GO:0008283 TAS cell proliferation
GO:0008469 IBA histone-arginine N-methyltransferase activity
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0018216 IMP peptidyl-arginine methylation
GO:0019918 IMP peptidyl-arginine methylation, to symmetrical-dimethyl arginine
GO:0032922 ISS circadian regulation of gene expression
GO:0034660 TAS ncRNA metabolic process
GO:0034709 IDA methylosome
GO:0035243 IMP protein-arginine omega-N symmetric methyltransferase activity
GO:0035246 IDA peptidyl-arginine N-methylation
GO:0042118 IMP endothelial cell activation
GO:0043021 IPI ribonucleoprotein complex binding
GO:0043985 ISS histone H4-R3 methylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023873 Prmt5-001 protein_coding Mus_musculus 0 2095
ENSMUST00000132227 Prmt5-003 nonsense_mediated_decay Mus_musculus 0 1064
ENSMUST00000139964 Prmt5-007 protein_coding Mus_musculus 0 636
ENSMUST00000133552 Prmt5-002 retained_intron Mus_musculus 0 435
ENSMUST00000132801 Prmt5-005 processed_transcript Mus_musculus 0 387
ENSMUST00000147214 Prmt5-004 retained_intron Mus_musculus 0 226

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