C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: numb homolog (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000555238 NUMB-004 ENSG00000133961 9606 - 14:73275216-73458530 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P0 CIL_0008P0_0001 VISTA 14:72878760-73482269
CIL_0001TR CIL_0001TR_0001 CGP 14:73237497-73463642

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005769 IEA early endosome
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005925 IDA focal adhesion
GO:0007219 TAS Notch signaling pathway
GO:0007399 IEA nervous system development
GO:0007405 IEA neuroblast proliferation
GO:0007409 IEA axonogenesis
GO:0007411 TAS axon guidance
GO:0008013 IEA beta-catenin binding
GO:0016323 IEA basolateral plasma membrane
GO:0019897 IEA extrinsic component of plasma membrane
GO:0021670 ISS lateral ventricle development
GO:0021849 ISS neuroblast division in subventricular zone
GO:0030136 IDA clathrin-coated vesicle
GO:0030335 IGI positive regulation of cell migration
GO:0030862 IEA positive regulation of polarized epithelial cell differentiation
GO:0030900 IEA forebrain development
GO:0034332 IEA adherens junction organization
GO:0045177 IEA apical part of cell
GO:0045294 IEA alpha-catenin binding
GO:0045296 IEA cadherin binding
GO:0045746 IEA negative regulation of Notch signaling pathway
GO:0050769 ISS positive regulation of neurogenesis
GO:0060487 IEA lung epithelial cell differentiation
GO:1903077 IMP negative regulation of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000110298 Numb-007 nonsense_mediated_decay Mus_musculus 0 2784
ENSMUST00000129335 Numb-002 protein_coding Mus_musculus 0 2459
ENSMUST00000154043 Numb-003 protein_coding Mus_musculus 0 2121
ENSMUST00000085215 Numb-005 nonsense_mediated_decay Mus_musculus 0 1790
ENSMUST00000117217 Numb-001 protein_coding Mus_musculus 0 1583
ENSMUST00000021647 Numb-004 protein_coding Mus_musculus 0 1410
ENSMUST00000155112 Numb-006 protein_coding Mus_musculus 0 817
ENSMUST00000135962 Numb-008 protein_coding Mus_musculus 0 636
ENSMUST00000125089 Numb-011 retained_intron Mus_musculus 0 296
ENSMUST00000136848 Numb-009 protein_coding Mus_musculus 0 294
ENSMUST00000126943 Numb-010 protein_coding Mus_musculus 7.9874e-44 183

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