C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: zinc and ring finger 1, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000567962 ZNRF1-007 ENSG00000186187 9606 + 16:74999345-75108028 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonLungMuscleTestisENST00000567962
Transcript ID Adipose Adrenal Brain Colon Lung Muscle Testis
ENST00000567962 16.387±0.00 18.172±0.00 4.604±0.00 13.703±0.00 30.288±0.00 23.225±0.00 27.920±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002PJ CIL_0002PJ_0001 CGP 16:74712955-75000173
CIL_0002PH CIL_0002PH_0001 CGP 16:74871367-75110994
CIL_0004Y8 CIL_0004Y8_0002 CGP 16:74999030-75116771

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005764 IEA lysosome
GO:0005768 IDA endosome
GO:0005829 IDA cytosol
GO:0008270 IEA zinc ion binding
GO:0016020 IDA membrane
GO:0016874 IEA ligase activity
GO:0030054 IEA cell junction
GO:0031410 IEA cytoplasmic vesicle
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045202 IEA synapse
GO:0046872 IEA metal ion binding
GO:0070936 ISS protein K48-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168428 Znrf1-202 protein_coding Mus_musculus 0 1282
ENSMUST00000172856 Znrf1-001 protein_coding Mus_musculus 0 1282
ENSMUST00000095176 Znrf1-002 protein_coding Mus_musculus 0 1238
ENSMUST00000173506 Znrf1-003 protein_coding Mus_musculus 0 1142
ENSMUST00000171182 Znrf1-203 protein_coding Mus_musculus 0 841
ENSMUST00000166859 Znrf1-201 protein_coding Mus_musculus 0 444
ENSMUST00000173922 Znrf1-011 nonsense_mediated_decay Mus_musculus 0 444
ENSMUST00000174333 Znrf1-008 protein_coding Mus_musculus 0 444
ENSMUST00000174454 Znrf1-007 protein_coding Mus_musculus 0 444
ENSMUST00000174376 Znrf1-005 nonsense_mediated_decay Mus_musculus 0 444
ENSMUST00000173781 Znrf1-010 protein_coding Mus_musculus 0 412
ENSMUST00000173726 Znrf1-012 protein_coding Mus_musculus 0 305

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