C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Fyn proto-oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000099967 Fyn-002 ENSMUSG00000019843 10090 + 10:39369798-39565372 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000099967
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000099967 11.092±5.53 4.903±1.21 6.029±1.89 37.236±19.49 5.852±1.53 1.474±0.46 4.983±0.47 2.183±0.60 2.478±1.32 4.653±0.66 0.845±0.28 9.545±4.40 4.277±0.73 2.114±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000954 CIL_000954_0002 VISTA 10:39357714-39964005

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001664 IPI G-protein coupled receptor binding
GO:0001764 IMP neuron migration
GO:0001948 IEA glycoprotein binding
GO:0004672 IDA protein kinase activity
GO:0004713 IDA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0005768 IDA endosome
GO:0005829 TAS cytosol
GO:0005884 IDA actin filament
GO:0005886 IEA plasma membrane
GO:0006468 IMP protein phosphorylation
GO:0007166 IDA cell surface receptor signaling pathway
GO:0008360 IDA regulation of cell shape
GO:0010629 IMP negative regulation of gene expression
GO:0010976 IGI positive regulation of neuron projection development
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014069 IEA postsynaptic density
GO:0015631 IDA tubulin binding
GO:0016020 IEA membrane
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0030900 IMP forebrain development
GO:0032403 IEA protein complex binding
GO:0036120 IDA cellular response to platelet-derived growth factor stimulus
GO:0042177 IMP negative regulation of protein catabolic process
GO:0042493 IEA response to drug
GO:0042552 TAS myelination
GO:0042608 IEA T cell receptor binding
GO:0042609 IEA CD4 receptor binding
GO:0042610 IEA CD8 receptor binding
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0044325 IPI ion channel binding
GO:0045121 IEA membrane raft
GO:0045471 IGI response to ethanol
GO:0046777 IDA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0046875 IEA ephrin receptor binding
GO:0048813 IMP dendrite morphogenesis
GO:0050798 IMP activated T cell proliferation
GO:0050852 IEA T cell receptor signaling pathway
GO:0050966 IMP detection of mechanical stimulus involved in sensory perception of pain
GO:0051428 IEA peptide hormone receptor binding
GO:0070851 IEA growth factor receptor binding
GO:0071363 IEA cellular response to growth factor stimulus
GO:0071375 IEA cellular response to peptide hormone stimulus
GO:0071944 IDA cell periphery
GO:1900182 IDA positive regulation of protein localization to nucleus
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000229471 FYN-029 protein_coding Homo_sapiens 0 1598
ENST00000314574 YES1-003 protein_coding Homo_sapiens 0 405
ENST00000354650 FYN-001 protein_coding Homo_sapiens 0 3892
ENST00000358208 SRC-201 protein_coding Homo_sapiens 0 523
ENST00000368667 FYN-014 protein_coding Homo_sapiens 0 3011
ENST00000368678 FYN-017 protein_coding Homo_sapiens 0 1604
ENST00000368682 FYN-002 protein_coding Homo_sapiens 0 2268
ENST00000373558 SRC-005 protein_coding Homo_sapiens 0 523
ENST00000373567 SRC-002 protein_coding Homo_sapiens 0 523
ENST00000373578 SRC-001 protein_coding Homo_sapiens 0 523
ENST00000462598 FYN-010 protein_coding Homo_sapiens 0 333
ENST00000462856 FYN-011 protein_coding Homo_sapiens 0 1051
ENST00000467556 SRC-007 retained_intron Homo_sapiens 1.4013e-45 187
ENST00000467899 FYN-005 retained_intron Homo_sapiens 0 660
ENST00000467921 FYN-009 retained_intron Homo_sapiens 0 1013
ENST00000471959 FYN-008 retained_intron Homo_sapiens 0 732
ENST00000476769 FYN-016 processed_transcript Homo_sapiens 0 1014
ENST00000477066 SRC-004 processed_transcript Homo_sapiens 0 523
ENST00000477475 SRC-010 processed_transcript Homo_sapiens 3e-16 90
ENST00000484067 FYN-018 protein_coding Homo_sapiens 0 773
ENST00000487824 FYN-024 protein_coding Homo_sapiens 0 392
ENST00000491885 FYN-015 processed_transcript Homo_sapiens 0 638
ENST00000495927 FYN-006 retained_intron Homo_sapiens 0 424
ENST00000495935 FYN-007 retained_intron Homo_sapiens 0 440
ENST00000496864 FYN-004 retained_intron Homo_sapiens 0 1203
ENST00000517419 FYN-028 protein_coding Homo_sapiens 0 813
ENST00000518295 FYN-022 protein_coding Homo_sapiens 0 712
ENST00000518630 FYN-019 protein_coding Homo_sapiens 0 654
ENST00000520518 FYN-020 protein_coding Homo_sapiens 0 863
ENST00000521062 FYN-013 protein_coding Homo_sapiens 0 538
ENST00000521361 FYN-021 retained_intron Homo_sapiens 0 442
ENST00000523238 FYN-012 protein_coding Homo_sapiens 0 774
ENST00000523322 FYN-027 retained_intron Homo_sapiens 0 1051
ENST00000523570 FYN-023 protein_coding Homo_sapiens 0 610
ENST00000523574 FYN-025 protein_coding Homo_sapiens 0 708
ENST00000524310 FYN-026 protein_coding Homo_sapiens 0 732
ENST00000538466 FYN-201 protein_coding Homo_sapiens 0 2268
ENST00000577961 YES1-006 protein_coding Homo_sapiens 0 405
ENST00000584307 YES1-002 protein_coding Homo_sapiens 0 405

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