C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, cAMP-dependent, regulatory, type I, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000588188 PRKAR1A-006 ENSG00000108946 9606 + 17:68515400-68551319 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006GP CIL_0006GP_0001 CGP 17:68420948-68551319
CIL_0003AG CIL_0003AG_0002 CGP 17:68511780-68601389

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001932 IEA regulation of protein phosphorylation
GO:0004862 IDA cAMP-dependent protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005952 IEA cAMP-dependent protein kinase complex
GO:0006112 TAS energy reserve metabolic process
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008603 IDA:IEA cAMP-dependent protein kinase regulator activity
GO:0016020 IDA membrane
GO:0031588 IDA AMP-activated protein kinase complex
GO:0031625 IDA ubiquitin protein ligase binding
GO:0034199 TAS activation of protein kinase A activity
GO:0034236 IPI protein kinase A catalytic subunit binding
GO:0035556 TAS intracellular signal transduction
GO:0043234 IDA protein complex
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050796 TAS regulation of insulin secretion
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus
GO:2000480 IDA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000049527 Prkar1a-001 protein_coding Mus_musculus 0 1164
ENSMUST00000106677 Prkar1a-002 protein_coding Mus_musculus 0 1164
ENSMUST00000106676 Prkar1a-004 protein_coding Mus_musculus 0 499

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