C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, cAMP dependent regulatory, type I, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000049527 Prkar1a-001 ENSMUSG00000020612 10090 + 11:109650921-109669656 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049527
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049527 54.070±17.60 209.442±10.25 77.576±9.17 83.003±5.48 73.579±29.13 52.130±8.60 70.242±7.16 63.574±4.25 42.792±3.63 104.368±7.67 19.171±2.06 100.313±17.57 37.177±9.38 38.296±6.66

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006GP CIL_0006GP_0002 CGP 11:109573331-109669656
CIL_0003AG CIL_0003AG_0003 CGP 11:109649405-109722279

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001707 IMP mesoderm formation
GO:0005515 IPI protein binding
GO:0005737 TAS cytoplasm
GO:0005886 IEA plasma membrane
GO:0006468 TAS protein phosphorylation
GO:0006469 IMP negative regulation of protein kinase activity
GO:0007507 IMP heart development
GO:0008283 TAS cell proliferation
GO:0008603 IGI cAMP-dependent protein kinase regulator activity
GO:0009887 TAS organ morphogenesis
GO:0031594 IDA neuromuscular junction
GO:0045214 IMP sarcomere organization
GO:0060038 IMP cardiac muscle cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000005587 prkar1ab-201 protein_coding Danio_rerio 0 750
ENST00000358598 PRKAR1A-004 protein_coding Homo_sapiens 0 1628
ENST00000392710 PRKAR1A-003 nonsense_mediated_decay Homo_sapiens 0 1602
ENST00000392711 PRKAR1A-201 protein_coding Homo_sapiens 0 1626
ENST00000441422 PRKAR1AP-001 processed_pseudogene Homo_sapiens 0 863
ENST00000536854 PRKAR1A-002 protein_coding Homo_sapiens 0 1626
ENST00000585427 PRKAR1A-010 protein_coding Homo_sapiens 0 473
ENST00000585460 PRKAR1A-018 retained_intron Homo_sapiens 0 580
ENST00000585608 PRKAR1A-017 nonsense_mediated_decay Homo_sapiens 0 852
ENST00000585815 PRKAR1A-015 protein_coding Homo_sapiens 1.4013e-45 187
ENST00000585907 PRKAR1A-007 retained_intron Homo_sapiens 0 405
ENST00000585981 PRKAR1A-013 protein_coding Homo_sapiens 0 1068
ENST00000586397 PRKAR1A-005 protein_coding Homo_sapiens 0 1478
ENST00000586541 PRKAR1A-020 nonsense_mediated_decay Homo_sapiens 0 468
ENST00000588178 PRKAR1A-016 protein_coding Homo_sapiens 0 584
ENST00000588188 PRKAR1A-006 protein_coding Homo_sapiens 0 1164
ENST00000588702 PRKAR1A-011 protein_coding Homo_sapiens 0 512
ENST00000589017 PRKAR1A-008 protein_coding Homo_sapiens 0 684
ENST00000589228 PRKAR1A-001 protein_coding Homo_sapiens 0 1698
ENST00000589480 PRKAR1A-014 protein_coding Homo_sapiens 0 296
ENST00000592800 PRKAR1A-019 protein_coding Homo_sapiens 0 529

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