C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor subfamily 1, group H, member 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000616973 NR1H3-201 ENSG00000025434 9606 + 11:47248300-47269032 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; OvaryPlacentaENST00000616973
Transcript ID Ovary Placenta
ENST00000616973 4.495±0.00 7.715±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0010875 IEA positive regulation of cholesterol efflux
GO:0010887 IEA negative regulation of cholesterol storage
GO:0030522 IEA intracellular receptor signaling pathway
GO:0042632 IEA cholesterol homeostasis
GO:0043031 IEA negative regulation of macrophage activation
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044255 IEA cellular lipid metabolic process
GO:0045861 IEA negative regulation of proteolysis
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050728 IEA negative regulation of inflammatory response
GO:0055088 IEA lipid homeostasis
GO:0055092 IEA sterol homeostasis
GO:0070328 IEA triglyceride homeostasis
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0090188 IEA negative regulation of pancreatic juice secretion
GO:0090341 IEA negative regulation of secretion of lysosomal enzymes
GO:2000188 IEA regulation of cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002177 Nr1h3-001 protein_coding Mus_musculus 0 1648
ENSMUST00000111356 Nr1h3-007 protein_coding Mus_musculus 0 1648
ENSMUST00000111354 Nr1h3-002 protein_coding Mus_musculus 0 1640
ENSMUST00000130031 Nr1h3-005 retained_intron Mus_musculus 0 944
ENSMUST00000111355 Nr1h3-003 protein_coding Mus_musculus 0 717
ENSMUST00000150654 Nr1h3-004 retained_intron Mus_musculus 0 717
ENSDART00000130731 nr1h3-203 protein_coding Danio_rerio 0 512
ENSDART00000123268 nr1h3-202 protein_coding Danio_rerio 0 512

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