C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor subfamily 1, group H, member 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000002177 Nr1h3-001 ENSMUSG00000002108 10090 - 2:91184061-91195116 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002177
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002177 24.032±8.43 8.396±2.42 4.706±0.02 0.645±0.08 11.151±2.31 3.035±0.00 3.287±0.17 10.460±1.30 18.064±11.24 17.184±1.56 2.987±1.45 3.236±0.78 4.021±3.56 1.627±0.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00017Z CIL_00017Z_0002 CGP 2:91137360-91202834

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006633 TAS fatty acid biosynthetic process
GO:0008270 IEA zinc ion binding
GO:0010875 IDA positive regulation of cholesterol efflux
GO:0010887 IGI negative regulation of cholesterol storage
GO:0030522 IDA intracellular receptor signaling pathway
GO:0042632 IGI cholesterol homeostasis
GO:0043031 IDA negative regulation of macrophage activation
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044255 IDA cellular lipid metabolic process
GO:0045861 IMP negative regulation of proteolysis
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050728 IDA negative regulation of inflammatory response
GO:0055088 IGI lipid homeostasis
GO:0055092 IMP sterol homeostasis
GO:0070328 IMP triglyceride homeostasis
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0090188 IMP negative regulation of pancreatic juice secretion
GO:0090341 IMP negative regulation of secretion of lysosomal enzymes
GO:2000188 IMP regulation of cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000253727 NR1H2-001 protein_coding Homo_sapiens 0 366
ENST00000395397 NR1H3-031 protein_coding Homo_sapiens 0 1613
ENST00000405576 NR1H3-003 protein_coding Homo_sapiens 0 717
ENST00000405853 NR1H3-006 protein_coding Homo_sapiens 0 808
ENST00000407404 NR1H3-002 protein_coding Homo_sapiens 0 809
ENST00000411902 NR1H2-003 protein_coding Homo_sapiens 0 366
ENST00000412937 NR1H3-012 protein_coding Homo_sapiens 0 538
ENST00000419652 NR1H3-014 nonsense_mediated_decay Homo_sapiens 1e-19 100
ENST00000420369 NR1H3-019 nonsense_mediated_decay Homo_sapiens 0 662
ENST00000436029 NR1H3-016 protein_coding Homo_sapiens 0 719
ENST00000436778 NR1H3-007 protein_coding Homo_sapiens 0 684
ENST00000437276 NR1H3-017 protein_coding Homo_sapiens 8.40779e-45 183
ENST00000441012 NR1H3-030 protein_coding Homo_sapiens 0 1670
ENST00000444396 NR1H3-010 protein_coding Homo_sapiens 0 673
ENST00000449369 NR1H3-013 protein_coding Homo_sapiens 0 697
ENST00000457932 NR1H3-011 protein_coding Homo_sapiens 0 209
ENST00000461778 NR1H3-015 processed_transcript Homo_sapiens 0 222
ENST00000462051 NR1H3-024 retained_intron Homo_sapiens 0 383
ENST00000467728 NR1H3-001 protein_coding Homo_sapiens 0 1714
ENST00000473222 NR1H3-022 processed_transcript Homo_sapiens 0 405
ENST00000476086 NR1H3-038 processed_transcript Homo_sapiens 0 481
ENST00000481020 NR1H3-005 retained_intron Homo_sapiens 0 942
ENST00000481889 NR1H3-023 protein_coding Homo_sapiens 0 942
ENST00000483882 NR1H3-021 retained_intron Homo_sapiens 0 355
ENST00000494018 NR1H3-025 retained_intron Homo_sapiens 0 383
ENST00000495866 NR1H3-026 processed_transcript Homo_sapiens 0 252
ENST00000498548 NR1H3-018 retained_intron Homo_sapiens 0 211
ENST00000525441 NR1H3-039 processed_transcript Homo_sapiens 0 211
ENST00000527464 NR1H3-028 processed_transcript Homo_sapiens 0 1009
ENST00000527949 NR1H3-032 protein_coding Homo_sapiens 0 676
ENST00000529540 NR1H3-029 processed_transcript Homo_sapiens 0 1618
ENST00000530310 NR1H3-035 processed_transcript Homo_sapiens 0 470
ENST00000531660 NR1H3-037 protein_coding Homo_sapiens 0 278
ENST00000532630 NR1H3-036 processed_transcript Homo_sapiens 0 540
ENST00000593532 NR1H2-010 nonsense_mediated_decay Homo_sapiens 0 259
ENST00000593926 NR1H2-002 protein_coding Homo_sapiens 0 366
ENST00000597085 NR1H2-013 retained_intron Homo_sapiens 0 248
ENST00000598168 NR1H2-014 protein_coding Homo_sapiens 0 279
ENST00000599105 NR1H2-005 protein_coding Homo_sapiens 0 259
ENST00000616973 NR1H3-201 protein_coding Homo_sapiens 0 1648

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