C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adaptor-related protein complex 2, beta 1 subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000621914 AP2B1-019 ENSG00000006125 9606 + 17:35587274-35726409 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000621914
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000621914 17.949±0.00 8.177±0.00 6.385±0.00 35.107±22.27 14.006±7.22 13.111±3.32 8.322±6.21 20.190±17.54 4.765±0.89 17.332±9.16 8.108±0.00 17.194±6.76 28.939±4.13 15.837±1.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003JS CIL_0003JS_0001 CGP 17:35548125-35578863
CIL_0003JV CIL_0003JV_0001 CGP 17:35574795-35726409

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006886 IEA intracellular protein transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008565 IEA protein transporter activity
GO:0015031 IEA protein transport
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016192 IEA vesicle-mediated transport
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030117 IEA membrane coat
GO:0030131 IEA clathrin adaptor complex
GO:0030276 IPI clathrin binding
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050690 TAS regulation of defense response to virus by virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000065692 Ap2b1-005 protein_coding Mus_musculus 0 4290
ENSMUST00000018875 Ap2b1-001 protein_coding Mus_musculus 0 2968
ENSMUST00000176430 Ap2b1-007 protein_coding Mus_musculus 0 2898
ENSMUST00000132178 Ap2b1-003 retained_intron Mus_musculus 0 2375
ENSMUST00000121855 Gm12834-001 processed_pseudogene Mus_musculus 0 2254
ENSMUST00000176523 Ap2b1-006 protein_coding Mus_musculus 0 2226
ENSMUST00000009234 Ap1b1-201 protein_coding Mus_musculus 0 1356
ENSMUST00000101613 Ap1b1-002 protein_coding Mus_musculus 0 935
ENSMUST00000109897 Ap1b1-001 protein_coding Mus_musculus 0 935
ENSMUST00000176944 Ap2b1-004 protein_coding Mus_musculus 0 900
ENSMUST00000142680 Ap2b1-002 protein_coding Mus_musculus 0 230

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