C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pre-B-cell leukemia transcription factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000052150 pbx4 7955 + 3:53637984-53714491 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000104683 pbx4-001 53637984-53714491 protein_coding
  ENSDART00000156935 pbx4-002 53690791-53712514 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000104683ENSDART00000156935
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000104683 8.413±2.48 6.370±2.05 2.702±0.00 0.672±0.00 2.496±0.00
ENSDART00000156935 N/A N/A N/A 0.389±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004NP CIL_0004NP_0001 CGP 3:53637984-53730531

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001755 IMP neural crest cell migration
GO:0001764 IDA neuron migration
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 IC transcription factor complex
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007411 IDA axon guidance
GO:0007420 IMP brain development
GO:0030182 IMP neuron differentiation
GO:0030901 IGI midbrain development
GO:0030902 IGI hindbrain development
GO:0031016 IMP pancreas development
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 IGI positive regulation of transcription, DNA-dependent
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048666 IMP neuron development
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0048741 IGI skeletal muscle fiber development
GO:0060059 IGI embryonic retina morphogenesis in camera-type eye

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000105717 PBX4 pre-B-cell leukemia homeobox 4 protein_coding Homo_sapiens
ENSMUSG00000031860 Pbx4 pre B cell leukemia homeobox 4 protein_coding Mus_musculus

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