C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine hydroxymethyltransferase 1 (soluble)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000052816 shmt1 7955 - 3:40255711-40270853 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000074737 shmt1-001 40255711-40270853 protein_coding
  ENSDART00000132225 shmt1-002 40263143-40270839 protein_coding
  ENSDART00000141578 shmt1-003 40263106-40269878 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000074737
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000074737 2.270±0.46 3.666±0.42 30.815±26.24 11.538±0.00 3.731±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00058O CIL_00058O_0001 CGP 3:40250190-40270853

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004372 IEA glycine hydroxymethyltransferase activity
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0005829 IDA cytosol
GO:0006544 IEA glycine metabolic process
GO:0006563 IEA L-serine metabolic process
GO:0006730 IEA one-carbon metabolic process
GO:0008168 IEA methyltransferase activity
GO:0016740 IEA transferase activity
GO:0030170 IEA pyridoxal phosphate binding
GO:0032259 IEA methylation
GO:0035999 IEA tetrahydrofolate interconversion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000176974 SHMT1 serine hydroxymethyltransferase 1 (soluble) protein_coding Homo_sapiens
ENSMUSG00000020534 Shmt1 serine hydroxymethyltransferase 1 (soluble) protein_coding Mus_musculus

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