C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine hydroxymethyltransferase 1 (soluble)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSDART00000074737 shmt1-001 ENSDARG00000052816 7955 - 3:40255711-40270853 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000074737
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000074737 2.270±0.46 3.666±0.42 30.815±26.24 11.538±0.00 3.731±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00058O CIL_00058O_0001 CGP 3:40250190-40270853

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004372 IEA glycine hydroxymethyltransferase activity
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0005829 IDA cytosol
GO:0006544 IEA glycine metabolic process
GO:0006563 IEA L-serine metabolic process
GO:0006730 IEA one-carbon metabolic process
GO:0008168 IEA methyltransferase activity
GO:0016740 IEA transferase activity
GO:0030170 IEA pyridoxal phosphate binding
GO:0032259 IEA methylation
GO:0035999 IEA tetrahydrofolate interconversion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000316694 SHMT1-001 protein_coding Homo_sapiens 0 582
ENST00000352886 SHMT1-201 protein_coding Homo_sapiens 0 484
ENST00000354098 SHMT1-003 protein_coding Homo_sapiens 0 414
ENST00000419974 SHMT1P1-001 processed_pseudogene Homo_sapiens 0 363
ENST00000579558 SHMT1-008 retained_intron Homo_sapiens 0 285
ENST00000580002 SHMT1-006 nonsense_mediated_decay Homo_sapiens 0 484
ENST00000582653 SHMT1-009 protein_coding Homo_sapiens 0 220

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