C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenomatosis polyposis coli
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000058868 apc 7955 + 10:1878297-1921518 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000044432 apc-201 1878297-1920569 protein_coding
  ENSDART00000149956 apc-001 1878297-1921518 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000149956
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000149956 22.476±9.94 2.139±1.24 1.018±0.16 0.836±0.00 2.985±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005KL CIL_0005KL_0001 CGP 10:1772173-1921518

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000281 IEA mitotic cytokinesis
GO:0000776 ISS kinetochore
GO:0001501 IMP skeletal system development
GO:0001754 IMP eye photoreceptor cell differentiation
GO:0001889 IMP liver development
GO:0001947 IMP heart looping
GO:0003146 IMP heart jogging
GO:0003157 IMP endocardium development
GO:0003170 IMP heart valve development
GO:0003306 IMP Wnt receptor signaling pathway involved in heart development
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005813 ISS centrosome
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007026 IEA negative regulation of microtubule depolymerization
GO:0007050 IEA cell cycle arrest
GO:0007051 ISS spindle organization
GO:0008013 IEA beta-catenin binding
GO:0008017 IEA microtubule binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0016055 IEA Wnt receptor signaling pathway
GO:0016328 ISS lateral plasma membrane
GO:0016477 IEA cell migration
GO:0019887 ISS protein kinase regulator activity
GO:0022006 IMP zona limitans intrathalamica formation
GO:0030178 IEA negative regulation of Wnt receptor signaling pathway
GO:0030426 ISS growth cone
GO:0030855 IMP epithelial cell differentiation
GO:0030877 ISS beta-catenin destruction complex
GO:0030917 IMP midbrain-hindbrain boundary development
GO:0031016 IMP pancreas development
GO:0031017 IMP exocrine pancreas development
GO:0031018 IMP endocrine pancreas development
GO:0031290 IMP retinal ganglion cell axon guidance
GO:0035050 IMP embryonic heart tube development
GO:0035118 IMP embryonic pectoral fin morphogenesis
GO:0043065 IEA positive regulation of apoptotic process
GO:0044030 IMP regulation of DNA methylation
GO:0045859 ISS regulation of protein kinase activity
GO:0048384 IGI retinoic acid receptor signaling pathway
GO:0048565 IMP digestive tract development
GO:0048920 IMP posterior lateral line neuromast primordium migration
GO:0055001 IGI muscle cell development
GO:0055123 IMP digestive system development
GO:0060041 IMP retina development in camera-type eye
GO:0060070 IMP canonical Wnt receptor signaling pathway
GO:0061031 IMP endodermal digestive tract morphogenesis
GO:0061380 IMP superior colliculus development
GO:0070365 IMP hepatocyte differentiation
GO:0071599 IMP otic vesicle development
GO:0090090 IGI negative regulation of canonical Wnt receptor signaling pathway
GO:0090244 IGI Wnt receptor signaling pathway involved in somitogenesis
GO:1900052 IGI regulation of retinoic acid biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000134982 APC adenomatous polyposis coli protein_coding Homo_sapiens
ENSG00000258864 CTC-554D6.1 protein_coding Homo_sapiens
ENSMUSG00000005871 Apc adenomatosis polyposis coli protein_coding Mus_musculus

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