C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium channel, voltage-gated, type IV, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000007314 SCN4A 9606 - 17:63938554-63972918 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000435607 SCN4A-201 63938554-63972918 protein_coding
  ENST00000578147 SCN4A-001 63938554-63972918 protein_coding
  ENST00000581514 SCN4A-002 63959373-63961693 retained_intron
  ENST00000584310 SCN4A-003 63947954-63949704 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonLiverLungMuscleOvaryPlacentaTestisENST00000435607ENST00000578147ENST00000581514ENST00000584310
Transcript ID Bladder Brain Breast Colon Liver Lung Muscle Ovary Placenta Testis
ENST00000435607 0.049±0.00 0.010±0.01 0.302±0.00 0.012±0.00 N/A N/A 8.992±0.00 0.036±0.00 0.064±0.01 N/A
ENST00000578147 N/A 0.010±0.01 0.640±0.00 N/A N/A 0.035±0.00 5.805±0.00 N/A 0.053±0.00 0.366±0.00
ENST00000581514 N/A N/A N/A 0.638±0.00 N/A N/A N/A N/A N/A N/A
ENST00000584310 N/A N/A N/A N/A 0.621±0.00 0.119±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B9 CIL_0009B9_0001 VISTA 17:63374232-63977730
CIL_0006Q8 CIL_0006Q8_0001 CGP 17:63928740-63972918
CIL_0002P3 CIL_0002P3_0001 CGP 17:63938554-64004304

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 IBA:IEA voltage-gated sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 IBA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0006814 TAS:IEA sodium ion transport
GO:0006936 TAS muscle contraction
GO:0016020 IEA membrane
GO:0019228 IBA neuronal action potential
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IBA sodium ion transmembrane transport
GO:0055085 IEA transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008797 scn4aa sodium channel, voltage-gated, type IV, alpha, a protein_coding Danio_rerio
ENSDARG00000034588 scn4ab sodium channel, voltage-gated, type IV, alpha, b protein_coding Danio_rerio
ENSMUSG00000001027 Scn4a sodium channel, voltage-gated, type IV, alpha protein_coding Mus_musculus

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