C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium channel, voltage-gated, type IV, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001027 Scn4a 10090 - 11:106318592-106353288 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021056 Scn4a-001 106318592-106349389 protein_coding
  ENSMUST00000174877 Scn4a-002 106349455-106353288 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021056ENSMUST00000174877
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021056 0.025±0.01 0.016±0.01 0.047±0.00 0.012±0.01 5.176±0.00 0.047±0.03 1.827±0.38 0.098±0.08 0.013±0.01 0.346±0.18 11.937±2.29 0.094±0.06 0.074±0.12 0.081±0.01
ENSMUST00000174877 0.119±0.00 0.261±0.00 N/A 0.077±0.00 N/A N/A N/A N/A N/A 0.822±0.00 N/A 0.140±0.04 0.067±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B9 CIL_0009B9_0002 VISTA 11:105834084-106435839
CIL_0006Q8 CIL_0006Q8_0002 CGP 11:106311341-106353288
CIL_0002P3 CIL_0002P3_0002 CGP 11:106318592-106377558

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IC voltage-gated sodium channel complex
GO:0005248 IDA voltage-gated sodium channel activity
GO:0005886 IBA plasma membrane
GO:0006814 IDA sodium ion transport
GO:0019228 IBA neuronal action potential
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008797 scn4aa sodium channel, voltage-gated, type IV, alpha, a protein_coding Danio_rerio
ENSDARG00000034588 scn4ab sodium channel, voltage-gated, type IV, alpha, b protein_coding Danio_rerio
ENSG00000007314 SCN4A sodium channel, voltage-gated, type IV, alpha subunit protein_coding Homo_sapiens

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