C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gamma-aminobutyric acid (GABA) A receptor, alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000022355 GABRA1 9606 + 5:161847191-161899969 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000023897 GABRA1-002 161847191-161897666 protein_coding
  ENST00000393943 GABRA1-005 161847934-161897666 protein_coding
  ENST00000428797 GABRA1-001 161847679-161899969 protein_coding
  ENST00000437025 GABRA1-004 161848444-161899954 protein_coding
  ENST00000519542 GABRA1-009 161873098-161891002 retained_intron
  ENST00000519621 GABRA1-008 161850597-161873230 protein_coding
  ENST00000521339 GABRA1-006 161848892-161865788 protein_coding
  ENST00000522651 GABRA1-007 161850386-161865789 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonKidneyLiverMusclePlacentaTestisENST00000023897ENST00000393943ENST00000428797ENST00000437025ENST00000519542ENST00000521339
Transcript ID Adrenal Bladder Brain Breast Colon Kidney Liver Muscle Placenta Testis
ENST00000023897 0.026±0.00 N/A N/A 0.004±0.00 N/A N/A N/A N/A N/A N/A
ENST00000393943 N/A N/A 18.022±0.00 N/A N/A N/A N/A N/A N/A 0.152±0.00
ENST00000428797 N/A 0.036±0.00 19.009±14.08 N/A N/A N/A N/A N/A N/A N/A
ENST00000437025 0.033±0.00 N/A 24.188±0.00 0.003±0.00 0.017±0.00 0.013±0.00 N/A 0.016±0.00 0.040±0.00 0.040±0.00
ENST00000519542 N/A N/A N/A N/A N/A N/A 0.109±0.00 N/A N/A N/A
ENST00000521339 N/A N/A N/A N/A N/A N/A 0.224±0.00 N/A 0.122±0.00 0.119±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016Q CIL_00016Q_0002 CGP 5:161547063-161899969
CIL_00016P CIL_00016P_0002 CGP 5:161847191-162155536

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004890 IEA GABA-A receptor activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005254 IEA chloride channel activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0006810 TAS:IEA transport
GO:0006811 IEA ion transport
GO:0007165 IEA signal transduction
GO:0007214 IEA gamma-aminobutyric acid signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008144 ISS drug binding
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016917 ISS GABA receptor activity
GO:0030054 IEA cell junction
GO:0034220 IEA:TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0045211 IEA postsynaptic membrane
GO:0051932 ISS synaptic transmission, GABAergic
GO:0055085 TAS transmembrane transport
GO:0071420 IEA cellular response to histamine
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068989 gabra1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 protein_coding Danio_rerio
ENSMUSG00000010803 Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 protein_coding Mus_musculus

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