C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000047315 POLR2B 9606 + 4:56977722-57031168 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000314595 POLR2B-201 56978943-57031168 protein_coding
  ENST00000381227 POLR2B-001 56977742-57031158 protein_coding
  ENST00000431623 POLR2B-014 56978864-57031158 protein_coding
  ENST00000433463 POLR2B-005 56978896-56990906 protein_coding
  ENST00000441246 POLR2B-006 56978869-57031007 protein_coding
  ENST00000450656 POLR2B-003 56977722-56990847 protein_coding
  ENST00000464918 POLR2B-010 57023227-57023751 retained_intron
  ENST00000478188 POLR2B-002 57009559-57031158 retained_intron
  ENST00000484821 POLR2B-011 57023491-57024962 retained_intron
  ENST00000495311 POLR2B-004 56977782-56978961 retained_intron
  ENST00000497845 POLR2B-007 56978904-56986803 retained_intron
  ENST00000510355 POLR2B-008 57010173-57015658 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000314595ENST00000381227ENST00000431623ENST00000441246ENST00000464918ENST00000510355
Transcript ID Adipose Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000314595 N/A N/A N/A N/A 5.093±0.00 7.374±0.00 N/A N/A N/A 14.122±1.99 11.731±1.19 7.975±0.00
ENST00000381227 N/A 6.213±0.00 N/A 8.872±0.00 N/A N/A 8.598±0.00 13.464±0.00 N/A N/A N/A N/A
ENST00000431623 N/A N/A 8.296±0.00 N/A 5.186±0.00 N/A N/A N/A N/A N/A N/A 8.077±0.00
ENST00000441246 12.665±0.00 N/A 17.999±0.00 14.781±0.00 19.147±0.00 N/A 7.920±0.00 N/A 17.595±0.00 N/A N/A N/A
ENST00000464918 N/A N/A N/A N/A N/A N/A N/A N/A N/A 89.608±0.00 75.951±0.00 100.598±0.00
ENST00000510355 N/A N/A N/A N/A N/A N/A N/A N/A N/A 54.278±0.00 50.335±0.00 68.650±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G9 CIL_0008G9_0001 VISTA 4:56396035-56999166
CIL_0003EC CIL_0003EC_0002 CGP 4:56907876-56978823
CIL_0003E8 CIL_0003E8_0002 CGP 4:56963370-57031168
CIL_0001WP CIL_0001WP_0001 CGP 4:56977722-57110385

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003899 IEA DNA-directed RNA polymerase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005665 IDA DNA-directed RNA polymerase II, core complex
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006351 IEA transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0032549 IEA ribonucleoside binding
GO:0044822 IDA poly(A) RNA binding
GO:0046872 IEA metal ion binding
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012592 polr2b polymerase (RNA) II (DNA directed) polypeptide B protein_coding Danio_rerio
ENSMUSG00000029250 Polr2b polymerase (RNA) II (DNA directed) polypeptide B protein_coding Mus_musculus

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