C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAD51 recombinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000051180 RAD51 9606 + 15:40694774-40732339 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000267868 RAD51-001 40695160-40732339 protein_coding
  ENST00000382643 RAD51-009 40695174-40731593 protein_coding
  ENST00000423169 RAD51-002 40695129-40731592 protein_coding
  ENST00000525066 RAD51-004 40695187-40731557 nonsense_mediated_decay
  ENST00000526763 RAD51-006 40695463-40701201 protein_coding
  ENST00000527860 RAD51-007 40694774-40718886 protein_coding
  ENST00000531277 RAD51-010 40698757-40729634 nonsense_mediated_decay
  ENST00000532743 RAD51-008 40695174-40731416 protein_coding
  ENST00000533741 RAD51-013 40701131-40718827 nonsense_mediated_decay
  ENST00000557850 RAD51-003 40695172-40731590 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000267868ENST00000382643ENST00000423169ENST00000525066ENST00000527860ENST00000531277ENST00000532743ENST00000533741ENST00000557850
Transcript ID Adipose Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000267868 N/A N/A 0.460±0.00 0.300±0.00 N/A N/A N/A N/A N/A 1.438±0.64 N/A
ENST00000382643 N/A N/A N/A N/A N/A 0.290±0.00 N/A N/A N/A N/A N/A
ENST00000423169 N/A N/A N/A 0.595±0.00 N/A N/A N/A 0.304±0.00 N/A 2.279±0.83 7.723±0.99
ENST00000525066 N/A N/A N/A N/A N/A N/A N/A N/A 2.784±0.00 2.904±0.06 N/A
ENST00000527860 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.127±0.00 N/A
ENST00000531277 N/A N/A N/A N/A N/A N/A N/A 0.962±0.00 N/A N/A N/A
ENST00000532743 0.332±0.00 N/A N/A N/A N/A N/A N/A N/A 1.182±0.00 1.628±0.00 N/A
ENST00000533741 N/A N/A N/A N/A N/A N/A N/A 0.421±0.00 N/A N/A N/A
ENST00000557850 N/A 0.138±0.00 N/A N/A 0.247±0.00 N/A 0.348±0.00 N/A 2.352±0.00 2.261±0.53 5.139±0.89

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005IO CIL_0005IO_0002 CGP 15:40694774-40755851

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000228 IDA nuclear chromosome
GO:0000724 TAS double-strand break repair via homologous recombination
GO:0000730 TAS DNA recombinase assembly
GO:0000793 ISS condensed chromosome
GO:0000794 ISS condensed nuclear chromosome
GO:0000800 IEA lateral element
GO:0003677 IEA DNA binding
GO:0003684 IEA damaged DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0003697 IDA:IEA single-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005856 IEA cytoskeleton
GO:0006200 IEA ATP catabolic process
GO:0006259 IEA DNA metabolic process
GO:0006268 IDA DNA unwinding involved in DNA replication
GO:0006281 IEA:TAS DNA repair
GO:0006302 TAS double-strand break repair
GO:0006310 TAS DNA recombination
GO:0006312 TAS mitotic recombination
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007126 ISS meiotic nuclear division
GO:0007131 TAS reciprocal meiotic recombination
GO:0008022 IPI protein C-terminus binding
GO:0008094 IEA DNA-dependent ATPase activity
GO:0009432 IEA SOS response
GO:0010569 IDA regulation of double-strand break repair via homologous recombination
GO:0016605 IDA PML body
GO:0042802 IPI identical protein binding
GO:0043142 IDA single-stranded DNA-dependent ATPase activity
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051106 IDA positive regulation of DNA ligation
GO:0051260 IPI protein homooligomerization
GO:0070182 IPI DNA polymerase binding
GO:0071479 IDA cellular response to ionizing radiation
GO:0072757 IDA cellular response to camptothecin

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041411 rad51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000027323 Rad51 RAD51 homolog protein_coding Mus_musculus

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