C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: laminin, alpha 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000053747 LAMA3 9606 + 18:23689443-23955066 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000269217 LAMA3-002 23872840-23954939 protein_coding
  ENST00000313654 LAMA3-001 23689443-23955066 protein_coding
  ENST00000399516 LAMA3-003 23689684-23954648 protein_coding
  ENST00000585600 LAMA3-005 23689598-23796148 non_stop_decay
  ENST00000586709 LAMA3-007 23898737-23899700 retained_intron
  ENST00000586751 LAMA3-011 23884773-23931559 protein_coding
  ENST00000587184 LAMA3-004 23873045-23954648 protein_coding
  ENST00000588004 LAMA3-012 23949893-23954799 protein_coding
  ENST00000588164 LAMA3-010 23928625-23931691 protein_coding
  ENST00000588770 LAMA3-006 23898261-23954989 processed_transcript
  ENST00000590104 LAMA3-014 23946184-23946837 protein_coding
  ENST00000591749 LAMA3-015 23827404-23837312 retained_intron
  ENST00000592442 LAMA3-008 23931155-23932585 retained_intron
  ENST00000592519 LAMA3-016 23833953-23834837 protein_coding
  ENST00000616172 LAMA3-201 23689598-23955063 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000269217ENST00000313654ENST00000399516ENST00000586709ENST00000586751ENST00000587184ENST00000588004ENST00000588164ENST00000588770ENST00000616172
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000269217 0.383±0.00 0.856±0.00 0.111±0.00 0.274±0.00 1.173±0.00 2.028±1.59 0.657±0.57 0.819±0.00 0.642±0.52 4.741±0.00 N/A 2.022±1.05 22.848±12.68 1.803±0.00
ENST00000313654 N/A N/A N/A 0.281±0.00 0.768±0.06 N/A N/A 0.028±0.00 1.423±0.00 6.359±5.14 N/A 0.887±0.00 N/A N/A
ENST00000399516 0.878±0.00 0.518±0.00 N/A 0.149±0.00 N/A 0.313±0.00 0.469±0.00 0.253±0.00 N/A 1.039±0.00 0.095±0.00 N/A N/A 0.529±0.00
ENST00000586709 N/A N/A 0.576±0.00 N/A N/A N/A N/A 0.319±0.00 N/A N/A N/A N/A N/A N/A
ENST00000586751 N/A N/A N/A N/A 2.611±0.00 1.029±0.00 N/A N/A 1.504±0.00 N/A N/A 3.539±0.00 N/A N/A
ENST00000587184 0.593±0.00 1.080±0.00 0.154±0.00 N/A 2.668±0.00 1.072±0.00 N/A 0.546±0.00 N/A 1.977±0.00 0.405±0.00 2.901±0.00 6.461±0.00 1.156±0.00
ENST00000588004 N/A 6.705±0.00 N/A N/A 13.289±0.00 N/A N/A N/A 1.112±0.00 22.288±0.00 N/A N/A N/A N/A
ENST00000588164 N/A N/A 0.979±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000588770 0.741±0.00 0.765±0.00 N/A N/A 1.313±0.00 N/A N/A 0.344±0.15 0.177±0.00 N/A N/A 2.535±0.50 11.829±5.77 1.148±0.00
ENST00000616172 N/A 0.612±0.00 N/A N/A N/A 0.294±0.00 N/A 0.039±0.00 0.027±0.00 N/A N/A 0.757±0.16 N/A 0.645±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005AV CIL_0005AV_0001 CGP 18:23598926-23955066
CIL_0005WU CIL_0005WU_0001 CGP 18:23689443-24135610

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005102 IEA receptor binding
GO:0005198 NAS structural molecule activity
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005604 TAS basement membrane
GO:0005606 IEA laminin-1 complex
GO:0005610 IEA laminin-5 complex
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007155 IEA cell adhesion
GO:0007165 IEA signal transduction
GO:0008544 TAS epidermis development
GO:0022617 TAS extracellular matrix disassembly
GO:0030155 IEA regulation of cell adhesion
GO:0030198 TAS extracellular matrix organization
GO:0030334 IEA regulation of cell migration
GO:0031581 TAS hemidesmosome assembly
GO:0034329 TAS cell junction assembly
GO:0035987 IEP endodermal cell differentiation
GO:0045995 IEA regulation of embryonic development
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022615 laminin, alpha 3 protein_coding Danio_rerio
ENSDARG00000071462 lama3 laminin, alpha 3 protein_coding Danio_rerio
ENSMUSG00000024421 Lama3 laminin, alpha 3 protein_coding Mus_musculus

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