C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysyl-tRNA synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000065427 KARS 9606 - 16:75627474-75648643 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302445 KARS-001 75627724-75647679 protein_coding
  ENST00000319410 KARS-002 75627474-75647665 protein_coding
  ENST00000562875 KARS-006 75631722-75647651 nonsense_mediated_decay
  ENST00000564578 KARS-004 75627770-75647648 nonsense_mediated_decay
  ENST00000565738 KARS-010 75639782-75641602 retained_intron
  ENST00000566249 KARS-008 75634241-75647607 nonsense_mediated_decay
  ENST00000566560 KARS-003 75633971-75648643 retained_intron
  ENST00000566772 KARS-011 75635324-75636073 protein_coding
  ENST00000568378 KARS-009 75627758-75647624 protein_coding
  ENST00000568682 KARS-007 75635699-75647650 protein_coding
  ENST00000569298 KARS-013 75627846-75629009 retained_intron
  ENST00000570215 KARS-012 75635791-75647655 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302445ENST00000319410ENST00000564578
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302445 51.270±0.00 58.730±0.00 5.968±0.00 19.819±8.54 27.903±12.36 38.049±21.28 23.589±14.95 24.395±15.33 19.192±5.89 27.380±16.11 75.719±59.18 30.418±20.26 40.819±14.90 61.579±26.55
ENST00000319410 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.561±0.00 N/A N/A
ENST00000564578 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.991±0.00 8.981±0.00 17.566±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002D7 CIL_0002D7_0001 CGP 16:75596981-75648643
CIL_0003YT CIL_0003YT_0001 CGP 16:75627474-75761872

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000049 NAS tRNA binding
GO:0000166 IEA nucleotide binding
GO:0003676 IEA nucleic acid binding
GO:0004812 IEA aminoacyl-tRNA ligase activity
GO:0004824 IDA:IEA lysine-tRNA ligase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005576 IEA extracellular region
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006418 TAS:IEA tRNA aminoacylation for protein translation
GO:0006430 IDA:IEA lysyl-tRNA aminoacylation
GO:0008033 NAS tRNA processing
GO:0008219 IEA cell death
GO:0010467 TAS gene expression
GO:0015630 IDA microtubule cytoskeleton
GO:0015966 IEA diadenosine tetraphosphate biosynthetic process
GO:0016032 IEA viral process
GO:0016597 IEA amino acid binding
GO:0017101 IEA aminoacyl-tRNA synthetase multienzyme complex
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044220 kars lysyl-tRNA synthetase protein_coding Danio_rerio
ENSMUSG00000031948 Kars lysyl-tRNA synthetase protein_coding Mus_musculus

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