C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: partner and localizer of BRCA2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000083093 PALB2 9606 - 16:23603160-23641310 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261584 PALB2-001 23603170-23641310 protein_coding
  ENST00000561514 PALB2-006 23636283-23640851 protein_coding
  ENST00000565038 PALB2-004 23624071-23637935 nonsense_mediated_decay
  ENST00000566069 PALB2-005 23603160-23621389 protein_coding
  ENST00000567003 PALB2-003 23636035-23641301 processed_transcript
  ENST00000568219 PALB2-002 23603168-23641285 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261584ENST00000566069ENST00000568219
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261584 0.831±0.00 0.698±0.00 N/A N/A 1.405±0.34 0.858±0.35 0.334±0.04 0.326±0.00 1.613±0.00 0.700±0.60 0.615±0.02 1.322±0.67 0.637±0.12 2.381±0.98
ENST00000566069 N/A 1.698±0.00 N/A N/A N/A 0.810±0.00 N/A N/A 1.311±0.00 N/A 1.159±0.00 1.379±0.00 0.751±0.00 3.381±0.00
ENST00000568219 N/A 0.567±0.00 0.220±0.00 1.436±0.00 N/A 0.367±0.00 0.614±0.00 1.337±0.00 0.650±0.00 N/A 0.605±0.00 1.072±0.44 1.414±0.00 4.339±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003VC CIL_0003VC_0002 CGP 16:23581002-23641310
CIL_0006D1 CIL_0006D1_0001 CGP 16:23603160-23677455

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000724 IDA double-strand break repair via homologous recombination
GO:0001756 IEA somitogenesis
GO:0001833 IEA inner cell mass cell proliferation
GO:0003677 IDA DNA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006281 TAS DNA repair
GO:0007498 IEA mesoderm development
GO:0009887 IEA organ morphogenesis
GO:0036342 IEA post-anal tail morphogenesis
GO:0043066 IEA negative regulation of apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076716 palb2 partner and localizer of BRCA2 protein_coding Danio_rerio
ENSMUSG00000044702 Palb2 partner and localizer of BRCA2 protein_coding Mus_musculus

Loading