C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 2B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000089094 KDM2B 9606 - 12:121429097-121581015 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377069 KDM2B-005 121429097-121580459 protein_coding
  ENST00000377071 KDM2B-001 121429777-121580984 protein_coding
  ENST00000446152 KDM2B-006 121509572-121579644 protein_coding
  ENST00000536036 KDM2B-023 121439913-121441244 retained_intron
  ENST00000536437 KDM2B-201 121429871-121580954 protein_coding
  ENST00000538046 KDM2B-004 121493846-121581015 protein_coding
  ENST00000538243 KDM2B-013 121444015-121470553 retained_intron
  ENST00000538379 KDM2B-015 121510007-121536069 protein_coding
  ENST00000538503 KDM2B-020 121429509-121549639 retained_intron
  ENST00000539394 KDM2B-007 121532846-121580225 protein_coding
  ENST00000540191 KDM2B-008 121574365-121580140 retained_intron
  ENST00000541318 KDM2B-014 121513328-121536128 protein_coding
  ENST00000541511 KDM2B-012 121521046-121536235 protein_coding
  ENST00000542030 KDM2B-017 121509943-121524795 protein_coding
  ENST00000542973 KDM2B-022 121429509-121509706 protein_coding
  ENST00000543025 KDM2B-002 121429871-121580954 nonsense_mediated_decay
  ENST00000543852 KDM2B-011 121516347-121537616 protein_coding
  ENST00000545022 KDM2B-016 121513293-121534660 protein_coding
  ENST00000611216 KDM2B-202 121429099-121581015 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastKidneyLiverMuscleOvaryPlacentaTestisENST00000377069ENST00000377071ENST00000538243ENST00000542973ENST00000611216
Transcript ID Adipose Adrenal Bladder Brain Breast Kidney Liver Muscle Ovary Placenta Testis
ENST00000377069 N/A N/A N/A 1.194±0.00 1.479±0.23 N/A N/A N/A 2.866±0.36 1.074±0.00 4.159±0.00
ENST00000377071 N/A N/A N/A N/A N/A N/A N/A N/A 5.926±0.00 N/A N/A
ENST00000538243 N/A N/A 0.772±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000542973 3.260±0.00 10.525±0.00 N/A N/A 2.732±0.49 2.079±0.68 1.455±0.19 1.692±0.00 12.974±7.37 4.888±1.94 7.494±0.26
ENST00000611216 N/A 5.961±0.00 N/A 3.850±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G3 CIL_0007G3_0002 CGP 12:121308245-121430623
CIL_0007G4 CIL_0007G4_0002 CGP 12:121400041-121581015
CIL_0007G5 CIL_0007G5_0003 CGP 12:121429097-121642677

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003677 NAS:IEA DNA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 NAS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007283 ISS spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016577 TAS histone demethylation
GO:0019843 IEA rRNA binding
GO:0021555 ISS midbrain-hindbrain boundary morphogenesis
GO:0021592 ISS fourth ventricle development
GO:0021670 ISS lateral ventricle development
GO:0021678 ISS third ventricle development
GO:0021993 ISS initiation of neural tube closure
GO:0030900 ISS forebrain development
GO:0030901 ISS midbrain development
GO:0030902 ISS hindbrain development
GO:0031519 IDA PcG protein complex
GO:0032452 TAS histone demethylase activity
GO:0035518 IDA histone H2A monoubiquitination
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0048596 ISS embryonic camera-type eye morphogenesis
GO:0051864 IEA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IEA histone H3-K36 demethylation
GO:2000178 ISS negative regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036593 kdm2ba lysine (K)-specific demethylase 2Ba protein_coding Danio_rerio
ENSDARG00000046010 kdm2bb lysine (K)-specific demethylase 2Bb protein_coding Danio_rerio
ENSMUSG00000029475 Kdm2b lysine (K)-specific demethylase 2B protein_coding Mus_musculus

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