C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 2B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000542973 KDM2B-022 ENSG00000089094 9606 - 12:121429509-121509706 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastKidneyLiverMuscleOvaryPlacentaTestisENST00000542973
Transcript ID Adipose Adrenal Breast Kidney Liver Muscle Ovary Placenta Testis
ENST00000542973 3.260±0.00 10.525±0.00 2.732±0.49 2.079±0.68 1.455±0.19 1.692±0.00 12.974±7.37 4.888±1.94 7.494±0.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G3 CIL_0007G3_0002 CGP 12:121308245-121430623
CIL_0007G4 CIL_0007G4_0002 CGP 12:121400041-121581015
CIL_0007G5 CIL_0007G5_0003 CGP 12:121429097-121642677

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003677 NAS DNA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 NAS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007283 ISS spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016577 TAS histone demethylation
GO:0019843 IEA rRNA binding
GO:0021555 ISS midbrain-hindbrain boundary morphogenesis
GO:0021592 ISS fourth ventricle development
GO:0021670 ISS lateral ventricle development
GO:0021678 ISS third ventricle development
GO:0021993 ISS initiation of neural tube closure
GO:0030900 ISS forebrain development
GO:0030901 ISS midbrain development
GO:0030902 ISS hindbrain development
GO:0031519 IDA PcG protein complex
GO:0032452 TAS histone demethylase activity
GO:0035518 IDA histone H2A monoubiquitination
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0048596 ISS embryonic camera-type eye morphogenesis
GO:0051864 IEA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IEA histone H3-K36 demethylation
GO:2000178 ISS negative regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000086200 Kdm2b-201 protein_coding Mus_musculus 0 3265
ENSMUST00000121739 Kdm2b-002 protein_coding Mus_musculus 0 3265
ENSMUST00000046073 Kdm2b-001 protein_coding Mus_musculus 0 3265
ENSMUST00000031435 Kdm2b-009 protein_coding Mus_musculus 0 3049
ENSMUST00000118027 Kdm2b-003 protein_coding Mus_musculus 0 1849
ENSMUST00000139674 Kdm2b-010 retained_intron Mus_musculus 0 1583
ENSMUST00000117674 Gm12397-001 processed_pseudogene Mus_musculus 0 859
ENSMUST00000132419 Kdm2b-017 retained_intron Mus_musculus 0 808
ENSMUST00000152872 Kdm2b-016 protein_coding Mus_musculus 0 769
ENSMUST00000173355 Kdm2b-019 processed_transcript Mus_musculus 0 695
ENSMUST00000123479 Kdm2b-005 retained_intron Mus_musculus 0 536
ENSMUST00000127403 Kdm2b-007 nonsense_mediated_decay Mus_musculus 0 536
ENSMUST00000129998 Kdm2b-008 processed_transcript Mus_musculus 0 460
ENSMUST00000174357 Kdm2b-018 retained_intron Mus_musculus 0 444
ENSDART00000053158 kdm2ba-201 protein_coding Danio_rerio 0 272

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