C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 2B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000377069 KDM2B-005 ENSG00000089094 9606 - 12:121429097-121580459 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastOvaryPlacentaTestisENST00000377069
Transcript ID Brain Breast Ovary Placenta Testis
ENST00000377069 1.194±0.00 1.479±0.23 2.866±0.36 1.074±0.00 4.159±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G3 CIL_0007G3_0002 CGP 12:121308245-121430623
CIL_0007G4 CIL_0007G4_0002 CGP 12:121400041-121581015
CIL_0007G5 CIL_0007G5_0003 CGP 12:121429097-121642677

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003677 NAS:IEA DNA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 NAS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007283 ISS spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016577 TAS histone demethylation
GO:0019843 IEA rRNA binding
GO:0021555 ISS midbrain-hindbrain boundary morphogenesis
GO:0021592 ISS fourth ventricle development
GO:0021670 ISS lateral ventricle development
GO:0021678 ISS third ventricle development
GO:0021993 ISS initiation of neural tube closure
GO:0030900 ISS forebrain development
GO:0030901 ISS midbrain development
GO:0030902 ISS hindbrain development
GO:0031519 IDA PcG protein complex
GO:0032452 TAS histone demethylase activity
GO:0035518 IDA histone H2A monoubiquitination
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0048596 ISS embryonic camera-type eye morphogenesis
GO:0051864 IEA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IEA histone H3-K36 demethylation
GO:2000178 ISS negative regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000118027 Kdm2b-003 protein_coding Mus_musculus 0 5182
ENSMUST00000046073 Kdm2b-001 protein_coding Mus_musculus 0 3212
ENSMUST00000086200 Kdm2b-201 protein_coding Mus_musculus 0 2833
ENSMUST00000121739 Kdm2b-002 protein_coding Mus_musculus 0 2833
ENSMUST00000123479 Kdm2b-005 retained_intron Mus_musculus 0 2508
ENSMUST00000127403 Kdm2b-007 nonsense_mediated_decay Mus_musculus 0 1853
ENSMUST00000031435 Kdm2b-009 protein_coding Mus_musculus 0 1772
ENSMUST00000156474 Kdm2b-006 protein_coding Mus_musculus 0 1746
ENSMUST00000134501 Kdm2b-004 retained_intron Mus_musculus 0 1605
ENSMUST00000139674 Kdm2b-010 retained_intron Mus_musculus 0 1580
ENSMUST00000145082 Kdm2b-013 protein_coding Mus_musculus 0 905
ENSMUST00000117674 Gm12397-001 processed_pseudogene Mus_musculus 0 782
ENSMUST00000152872 Kdm2b-016 protein_coding Mus_musculus 0 769
ENSMUST00000150543 Kdm2b-011 processed_transcript Mus_musculus 0 760
ENSMUST00000143273 Kdm2b-015 processed_transcript Mus_musculus 0 747
ENSMUST00000173355 Kdm2b-019 processed_transcript Mus_musculus 0 695
ENSMUST00000138929 Kdm2b-012 processed_transcript Mus_musculus 0 534
ENSMUST00000147544 Kdm2b-014 processed_transcript Mus_musculus 0 505
ENSMUST00000129998 Kdm2b-008 processed_transcript Mus_musculus 0 460
ENSMUST00000174357 Kdm2b-018 retained_intron Mus_musculus 0 444
ENSMUST00000132419 Kdm2b-017 retained_intron Mus_musculus 0 331
ENSDART00000053158 kdm2ba-201 protein_coding Danio_rerio 0 272

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