C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, heavy chain 7, cardiac muscle, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000092054 MYH7 9606 - 14:23412738-23435718 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355349 MYH7-001 23412738-23435718 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355349
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355349 0.043±0.00 0.038±0.00 0.198±0.00 0.382±0.25 45.431±43.79 0.489±0.37 935.981±0.00 0.071±0.01 3.717±3.39 0.900±0.89 938.781±360.42 0.159±0.10 7.369±7.29 30.600±29.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090C CIL_00090C_0001 VISTA 14:23078458-23681621
CIL_0009BW CIL_0009BW_0001 VISTA 14:23137378-23739005
CIL_0008Q4 CIL_0008Q4_0001 VISTA 14:23138150-23738498
CIL_0008QH CIL_0008QH_0001 VISTA 14:23142404-23743714
CIL_0004Z7 CIL_0004Z7_0007 CGP 14:23381990-23435718

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000146 IDA microfilament motor activity
GO:0001725 IEA stress fiber
GO:0002026 IDA regulation of the force of heart contraction
GO:0002027 IDA regulation of heart rate
GO:0003774 IEA motor activity
GO:0003779 IEA actin binding
GO:0005515 IPI:IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005859 TAS muscle myosin complex
GO:0005925 IDA focal adhesion
GO:0006200 IDA ATP catabolic process
GO:0006936 IDA muscle contraction
GO:0006941 IDA striated muscle contraction
GO:0007512 IMP adult heart development
GO:0016459 TAS:IEA myosin complex
GO:0016887 IDA ATPase activity
GO:0030016 IEA myofibril
GO:0030017 TAS sarcomere
GO:0030018 IEA Z disc
GO:0030049 IMP muscle filament sliding
GO:0030898 IMP actin-dependent ATPase activity
GO:0032982 IDA myosin filament
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045242 smyhc3 slow myosin heavy chain 3 protein_coding Danio_rerio
ENSDARG00000071430 smyhc1 slow myosin heavy chain 1 protein_coding Danio_rerio
ENSDARG00000071433 smyhc2 slow myosin heavy chain 2 protein_coding Danio_rerio
ENSDARG00000079564 vmhc ventricular myosin heavy chain protein_coding Danio_rerio
ENSDARG00000079782 vmhcl ventricular myosin heavy chain-like protein_coding Danio_rerio
ENSDARG00000092357 CU633479.5 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000092902 CR450736.2 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000093148 CU633479.6 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000093715 si:ch211-24n20.3 si:ch211-24n20.3 protein_coding Danio_rerio
ENSMUSG00000053093 Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta protein_coding Mus_musculus

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